Animal models of major depression: drawbacks and challenges
Major depression is a leading contributor to the global burden of disease. This situation is
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …
mainly related to the chronicity and/or recurrence of the disorder, and to poor response to …
[HTML][HTML] Role of stress in skin diseases: a neuroendocrine-immune interaction view
H Zhang, M Wang, X Zhao, Y Wang, X Chen… - Brain, behavior, and …, 2024 - Elsevier
Psychological stress is a crucial factor in the development of many skin diseases, and the
stigma caused by skin disorders may further increase the psychological burden, forming a …
stigma caused by skin disorders may further increase the psychological burden, forming a …
The dynamic state of a prefrontal–hypothalamic–midbrain circuit commands behavioral transitions
Innate behaviors meet multiple needs adaptively and in a serial order, suggesting the
existence of a hitherto elusive brain dynamics that brings together representations of …
existence of a hitherto elusive brain dynamics that brings together representations of …
Exploratory rearing: a context-and stress-sensitive behavior recorded in the open-field test
Stressful experiences are linked to anxiety disorders in humans. Similar effects are observed
in rodent models, where anxiety is often measured in classic conflict tests such as the open …
in rodent models, where anxiety is often measured in classic conflict tests such as the open …
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice
As human lifespan increases, a greater fraction of the population is suffering from age-
related cognitive impairments, making it important to elucidate a means to combat the effects …
related cognitive impairments, making it important to elucidate a means to combat the effects …
BLA to vHPC inputs modulate anxiety-related behaviors
The basolateral amygdala (BLA) and ventral hippocampus (vHPC) have both been
implicated in mediating anxiety-related behaviors, but the functional contribution of BLA …
implicated in mediating anxiety-related behaviors, but the functional contribution of BLA …
The tail suspension test
A Can, DT Dao, CE Terrillion… - Journal of …, 2012 - pmc.ncbi.nlm.nih.gov
The tail-suspension test is a mouse behavioral test useful in the screening of potential
antidepressant drugs, and assessing of other manipulations that are expected to affect …
antidepressant drugs, and assessing of other manipulations that are expected to affect …
The mouse forced swim test
The forced swim test is a rodent behavioral test used for evaluation of antidepressant drugs,
antidepressant efficacy of new compounds, and experimental manipulations that are aimed …
antidepressant efficacy of new compounds, and experimental manipulations that are aimed …
Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling
K Gouveia, JL Hurst - Scientific reports, 2017 - nature.com
Handling laboratory animals during test procedures is an important source of stress that may
impair reliability of test responses. Picking up mice by the tail is aversive, stimulating stress …
impair reliability of test responses. Picking up mice by the tail is aversive, stimulating stress …
[HTML][HTML] Gut microbiota suppress feeding induced by palatable foods
Feeding behaviors depend on intrinsic and extrinsic factors including genetics, food
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …
palatability, and the environment. 1, 2, 3, 4, 5 The gut microbiota is a major environmental …