Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Background The time course of blood lactate levels could be helpful to assess a patient's
response to therapy. Although the focus of published studies has been largely on septic …

Background Effective targeted therapy for sepsis requires an understanding of the
heterogeneity in the individual host response to infection. We investigated this heterogeneity …

In recent years, a new group of nanomaterials named nanozymes that exhibit enzyme-
mimicking catalytic activity has emerged as a promising alternative to natural enzymes …

Lactate levels are commonly evaluated in acutely ill patients. Although most often used in
the context of evaluating shock, lactate levels can be elevated for many reasons. While …

Lactate detection plays a significant role in healthcare, food industries and is specially
necessitated in conditions like hemorrhage, respiratory failure, hepatic disease, sepsis and …

Increased blood lactate levels, known as hyperlactatemia, are frequently observed in
critically ill patients. While elevated lactate is often used to diagnose inadequate tissue …

Purpose Hyperlactatemia may occur for a variety of reasons and is a predictor of poor
clinical outcome. However, only limited data are available on the underlying causes of …

Rationale: It is unknown whether lactate monitoring aimed to decrease levels during initial
treatment in critically ill patients improves outcome. Objectives: To assess the effect of lactate …

Objective: To test whether the association between initial serum lactate level and mortality in
patients presenting to the emergency department (ED) with severe sepsis is independent of …