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Noninvasive morpho-molecular imaging reveals early therapy-induced senescence in human cancer cells
Anticancer therapy screening in vitro identifies additional treatments and improves clinical
outcomes. Systematically, although most tested cells respond to cues with apoptosis, an …
outcomes. Systematically, although most tested cells respond to cues with apoptosis, an …
Raman spectroscopy and AI applications in cancer grading. An overview
Raman spectroscopy (RS) is a label-free molecular vibrational spectroscopy technique that
is able to identify the molecular fingerprint of various samples making use of the inelastic …
is able to identify the molecular fingerprint of various samples making use of the inelastic …
Full-spectrum CARS microscopy of cells and tissues with ultrashort white-light continuum pulses
Coherent anti-Stokes Raman scattering (CARS) microscopy is an emerging nonlinear
vibrational imaging technique that delivers label-free chemical maps of cells and tissues. In …
vibrational imaging technique that delivers label-free chemical maps of cells and tissues. In …
High-throughput multimodal wide-field Fourier-transform Raman microscope
Raman microscopy is a powerful analytical technique for materials and life sciences that
enables map** the spatial distribution of the chemical composition of a sample. State-of …
enables map** the spatial distribution of the chemical composition of a sample. State-of …
Fingerprint multiplex CARS at high speed based on supercontinuum generation in bulk media and deep learning spectral denoising
We introduce a broadband coherent anti-Stokes Raman scattering (CARS) microscope
based on a 2-MHz repetition rate ytterbium laser generating 1035-nm high-energy (≈ µJ …
based on a 2-MHz repetition rate ytterbium laser generating 1035-nm high-energy (≈ µJ …
[HTML][HTML] Broadband stimulated Raman imaging based on multi-channel lock-in detection for spectral histopathology
Spontaneous Raman microscopy reveals the chemical composition of a sample in a label-
free and non-invasive fashion by directly measuring the vibrational spectra of molecules …
free and non-invasive fashion by directly measuring the vibrational spectra of molecules …
Raman micro-spectroscopy reveals the spatial distribution of fumarate in cells and tissues
Aberrantly accumulated metabolites elicit intra-and inter-cellular pro-oncogenic cascades,
yet current measurement methods require sample perturbation/disruption and lack spatio …
yet current measurement methods require sample perturbation/disruption and lack spatio …
Self-referencing for quasi shot-noise-limited widefield transient microscopy
Many applications of ultrafast and nonlinear optical microscopy require the measurement of
small differential signals over large fields-of-view. Widefield configurations drastically reduce …
small differential signals over large fields-of-view. Widefield configurations drastically reduce …
A dual-modal, label-free Raman imaging method for rapid virtual staining of large-area breast cancer tissue sections
As one of the most common cancers, accurate, rapid, and simple histopathological
diagnosis is very important for breast cancer. Raman imaging is a powerful technique for …
diagnosis is very important for breast cancer. Raman imaging is a powerful technique for …
Simultaneous label-free autofluorescence multi-harmonic microscopy driven by the supercontinuum generated from a bulk nonlinear crystal
Nonlinear microscopy encompasses several imaging techniques that leverage laser
technology to probe intrinsic molecules of biological specimens. These native molecules …
technology to probe intrinsic molecules of biological specimens. These native molecules …