Pathophysiology of atherosclerosis

S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …

Heart disease and stroke statistics—2022 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, A Alonso… - Circulation, 2022 - ahajournals.org
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

Global epidemiology of dyslipidaemias

A Pirillo, M Casula, E Olmastroni, GD Norata… - Nature Reviews …, 2021 - nature.com
Dyslipidaemias are alterations to the plasma lipid profile that are often associated with
clinical conditions. Dyslipidaemias, particularly elevated plasma LDL-cholesterol levels, are …

Epidemiology of coronary artery disease

JP Duggan, AS Peters, GD Trachiotis… - Surgical …, 2022 - surgical.theclinics.com
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2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of …

F Mach, C Baigent, AL Catapano… - European heart …, 2020 - academic.oup.com
version of the Guidelines, which is freely available via the ESC and EAS websites and
hosted on their journals' websites (EHJ and Atherosclerosis Journal). The National Cardiac …

Efficacy and safety of statin therapy in older people: a meta-analysis of individual participant data from 28 randomised controlled trials

J Armitage, C Baigent, E Barnes, DJ Betteridge… - The Lancet, 2019 - thelancet.com
Background Statin therapy has been shown to reduce major vascular events and vascular
mortality in a wide range of individuals, but there is uncertainty about its efficacy and safety …

Elevated LDL cholesterol and increased risk of myocardial infarction and atherosclerotic cardiovascular disease in individuals aged 70–100 years: a contemporary …

MB Mortensen, BG Nordestgaard - The Lancet, 2020 - thelancet.com
Background Findings of historical studies suggest that elevated LDL cholesterol is not
associated with increased risk of myocardial infarction and atherosclerotic cardiovascular …

Disparities in cardiovascular mortality between Black and White adults in the United States, 1999 to 2019

AN Kyalwazi, EC Loccoh, LPC Brewer, EO Ofili, J Xu… - Circulation, 2022 - ahajournals.org
Background: Black adults experience a disproportionately higher burden of cardiovascular
risk factors and disease in comparison with White adults in the United States. Less is known …

Decline in cardiovascular mortality: possible causes and implications

GA Mensah, GS Wei, PD Sorlie, LJ Fine… - Circulation …, 2017 - ahajournals.org
If the control of infectious diseases was the public health success story of the first half of the
20th century, then the decline in mortality from coronary heart disease and stroke has been …

Cardiovascular risk factors associated with venous thromboembolism

J Gregson, S Kaptoge, T Bolton, L Pennells… - JAMA …, 2019 - jamanetwork.com
Importance It is uncertain to what extent established cardiovascular risk factors are
associated with venous thromboembolism (VTE). Objective To estimate the associations of …