[HTML][HTML] Challenges for biophysical modeling of microstructure
The biophysical modeling efforts in diffusion MRI have grown considerably over the past 25
years. In this review, we dwell on the various challenges along the journey of bringing a …
years. In this review, we dwell on the various challenges along the journey of bringing a …
Axon morphology is modulated by the local environment and impacts the noninvasive investigation of its structure–function relationship
Axonal conduction velocity, which ensures efficient function of the brain network, is related to
axon diameter. Noninvasive, in vivo axon diameter estimates can be made with diffusion …
axon diameter. Noninvasive, in vivo axon diameter estimates can be made with diffusion …
Susceptibility-induced internal gradients reveal axon morphology and cause anisotropic effects in the diffusion-weighted MRI signal
Diffusion-weighted MRI is our most promising method for estimating microscopic tissue
morphology in vivo. The signal acquisition is based on scanner-generated ex ternal …
morphology in vivo. The signal acquisition is based on scanner-generated ex ternal …
[HTML][HTML] Resolving bundle-specific intra-axonal T2 values within a voxel using diffusion-relaxation tract-based estimation
At the typical spatial resolution of MRI in the human brain, approximately 60–90% of voxels
contain multiple fiber populations. Quantifying microstructural properties of distinct fiber …
contain multiple fiber populations. Quantifying microstructural properties of distinct fiber …
Bundle-specific axon diameter index as a new contrast to differentiate white matter tracts
In the central nervous system of primates, several pathways are characterized by different
spectra of axon diameters. In vivo methods, based on diffusion-weighted magnetic …
spectra of axon diameters. In vivo methods, based on diffusion-weighted magnetic …
Fast multi-compartment Microstructure Fingerprinting in brain white matter
We proposed two deep neural network based methods to accelerate the estimation of
microstructural features of crossing fascicles in the white matter. Both methods focus on the …
microstructural features of crossing fascicles in the white matter. Both methods focus on the …
Cellular Exchange Imaging (CEXI): Evaluation of a diffusion model including water exchange in cells using numerical phantoms of permeable spheres
Purpose Biophysical models of diffusion MRI have been developed to characterize
microstructure in various tissues, but existing models are not suitable for tissue composed of …
microstructure in various tissues, but existing models are not suitable for tissue composed of …
[HTML][HTML] Does powder averaging remove dispersion bias in diffusion MRI diameter estimates within real 3D axonal architectures?
Noninvasive estimation of axon diameter with diffusion MRI holds the potential to investigate
the dynamic properties of the brain network and pathology of neurodegenerative diseases …
the dynamic properties of the brain network and pathology of neurodegenerative diseases …
[HTML][HTML] Physical and digital phantoms for validating tractography and assessing artifacts
Fiber tractography is widely used to non-invasively map white-matter bundles in vivo using
diffusion-weighted magnetic resonance imaging (dMRI). As it is the case for all scientific …
diffusion-weighted magnetic resonance imaging (dMRI). As it is the case for all scientific …
Molecular imaging with aquaporin-based reporter genes: quantitative considerations from Monte Carlo diffusion simulations
Aquaporins provide a unique approach for imaging genetic activity in deep tissues by
increasing the rate of cellular water diffusion, which generates a magnetic resonance …
increasing the rate of cellular water diffusion, which generates a magnetic resonance …