Design of Experiments and machine learning for product innovation: A systematic literature review

R Arboretti, R Ceccato, L Pegoraro… - Quality and Reliability …, 2022 - Wiley Online Library
The recent increase in digitalization of industrial systems has resulted in a boost in data
availability in the industrial environment. This has favored the adoption of machine learning …

A quality by design approach in oral extended release drug delivery systems: where we are and where we are going?

AS Sousa, J Serra, C Estevens, R Costa… - Journal of …, 2023 - Springer
Background Oral extended release (ER) delivery systems have quickly gained increasing
importance because of their ability to maintain drug levels in the blood more consistently …

[HTML][HTML] Real-time release testing of dissolution based on surrogate models developed by machine learning algorithms using NIR spectra, compression force and …

DL Galata, Z Könyves, B Nagy, M Novák… - International Journal of …, 2021 - Elsevier
In this work spectroscopic measurements, process data and Critical Material Attributes
(CMAs) are used to predict the in vitro dissolution profile of sustained-release tablets with …

A comparative study of multi-objective methods and algorithms for optimizing emulgels consistency and drug diffusion

MK Amar, S Rahal, M Laidi, H Boukessani… - Journal of Drug Delivery …, 2023 - Elsevier
The development of effective drug delivery systems is a challenging task that requires a
thorough understanding of various destabilization phenomena and the trade-offs between …

Ethanol-induced dose dum** from sodium alginate matrix tablets: Investigation of the effects of medium viscosity and pH

SA Rahim, N Al-Zoubi, H Khader, R Alwaraydat… - International Journal of …, 2023 - Elsevier
In this work, the swelling and disintegration of drug-free sodium alginate (SA) compacts and
the release of metformin HCl from SA matrix tablets were investigated in acidic media of …

A Study Using Optimized LSSVR for Real-Time Fault Detection of Liquid Rocket Engine

P Huang, H Yu, T Wang - Processes, 2022 - mdpi.com
Health monitoring and fault diagnosis of liquid rocket engine (LRE) are the most important
concerning issue for the safety of rocket's flying, especially for the man-carried aerospace …

Non-targeted metabolomic analysis of chicken kidneys in response to coronavirus IBV infection under stress induced by dexamethasone

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in Cellular …, 2022 - frontiersin.org
Stress in poultry can lead to changes in body metabolism and immunity, which can increase
susceptibility to infectious diseases. However, knowledge regarding chicken responses to …

[PDF][PDF] Application of innovative analytical techniques in pharmaceutical manufacturing Innovatív analitikai eljárások alkalmazása gyógyszerkészítmények előállítása …

DL Galata - repozitorium.omikk.bme.hu
In our aging society, reliable and affordable medical treatment becomes ever more
important. Recently the pharmaceutical industry has made its first steps toward the …

Application of Innovative Analytical Techniques in Pharmaceutical Manufacturing

DL Galata - 2021 - search.proquest.com
In our aging society, reliable and affordable medical treatment becomes ever more
important. Recently the pharmaceutical industry has made its first steps toward the …