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Circadian rhythm disruption and mental health
Circadian rhythms are internal manifestations of the solar day that permit adaptations to
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
predictable environmental temporal changes. These~ 24-h rhythms are controlled by …
The functional and clinical significance of the 24-hour rhythm of circulating glucocorticoids
Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …
Timing of light exposure affects mood and brain circuits
Temporal organization of physiology is critical for human health. In the past, humans
experienced predictable periods of daily light and dark driven by the solar day, which …
experienced predictable periods of daily light and dark driven by the solar day, which …
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
LN Vandenberg, T Colborn, TB Hayes… - Endocrine …, 2012 - academic.oup.com
For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …
How might circadian rhythms control mood? Let me count the ways...
CA McClung - Biological psychiatry, 2013 - Elsevier
Mood disorders are serious diseases that affect a large portion of the population. There have
been many hypotheses put forth over the years to explain the development of major …
been many hypotheses put forth over the years to explain the development of major …
Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses
N Schurhoff, M Toborek - Molecular brain, 2023 - Springer
Circadian disruption has become more prevalent in society due to the increase in shift work,
sleep disruption, blue light exposure, and travel via different time zones. The circadian …
sleep disruption, blue light exposure, and travel via different time zones. The circadian …
Circadian control of BDNF-mediated Nrf2 activation in astrocytes protects dopaminergic neurons from ferroptosis
T Ishii, E Warabi, GE Mann - Free Radical Biology and Medicine, 2019 - Elsevier
Astrocyte-neuron interactions protect neurons from iron-mediated toxicity. As dopamine can
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …
be metabolized to reactive quinones, dopaminergic neurons are susceptible to oxidative …
[HTML][HTML] Identification of a circadian output circuit for rest: activity rhythms in Drosophila
DJ Cavanaugh, JD Geratowski, JRA Wooltorton… - Cell, 2014 - cell.com
Though much is known about the cellular and molecular components of the circadian clock,
output pathways that couple clock cells to overt behaviors have not been identified. We …
output pathways that couple clock cells to overt behaviors have not been identified. We …
[HTML][HTML] Advances in understanding the peripheral circadian clocks
J Richards, ML Gumz - The FASEB Journal, 2012 - pmc.ncbi.nlm.nih.gov
In the past decade, it has become increasingly evident that the circadian clock system plays
an important role in many physiological processes. The circadian clock can be divided into 2 …
an important role in many physiological processes. The circadian clock can be divided into 2 …
The effects of shift work on physical and mental health
M Vogel, T Braungardt, W Meyer… - Journal of neural …, 2012 - Springer
Occupational engagement is a pre-requisite for continuous income opportunities. Among the
changing social circumstances work-related conditions play an increasingly eminent role in …
changing social circumstances work-related conditions play an increasingly eminent role in …