[HTML][HTML] Inferring signatures of positive selection in whole-genome sequencing data: an overview of haplotype-based methods

P Abondio, E Cilli, D Luiselli - Genes, 2022 - mdpi.com
Signatures of positive selection in the genome are a characteristic mark of adaptation that
can reveal an ongoing, recent, or ancient response to environmental change throughout the …

Personalized medicine and nutrition in hepatology for preventing chronic liver disease in Mexico

A Panduro, S Roman, IM Mariscal-Martinez… - Frontiers in …, 2024 - frontiersin.org
Chronic liver disease is a global health issue. Patients with chronic liver disease require a
fresh approach that focuses on the genetic and environmental factors that contribute to …

Ancient genomes reveal insights into ritual life at Chichén Itzá

R Barquera, O Del Castillo-Chávez, K Nägele… - Nature, 2024 - nature.com
The ancient city of Chichén Itzá in Yucatán, Mexico, was one of the largest and most
influential Maya settlements during the Late and Terminal Classic periods (ad 600–1000) …

Indigenous people from Amazon show genetic signatures of pathogen-driven selection

CM Couto-Silva, K Nunes, G Venturini… - Science …, 2023 - science.org
Ecological conditions in the Amazon rainforests are historically favorable for the
transmission of numerous tropical diseases, especially vector-borne diseases. The high …

[HTML][HTML] Hunter-gatherer admixture facilitated natural selection in Neolithic European farmers

T Davy, D Ju, I Mathieson, P Skoglund - Current Biology, 2023 - cell.com
Ancient DNA has revealed multiple episodes of admixture in human prehistory during
geographic expansions associated with cultural innovations. One important example is the …

Personalized nutrition: the end of the one-diet-fits-all era

S Roman, L Campos-Medina, L Leal-Mercado - Frontiers in Nutrition, 2024 - frontiersin.org
Personalized Nutrition emerged as a new trend for providing nutritional and food advice
based on the individual's genetic composition, a field driven by the advancements in the …

Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among native American …

R Torres-Valadez, S Roman… - World journal of …, 2022 - pmc.ncbi.nlm.nih.gov
BACKGROUND Dyslipidemias are metabolic abnormalities associated with chronic
diseases caused by genetic and environmental factors. The Mexican population displays …

Biogeographic Perspectives on Human Genetic Diversification

T Hünemeier - Molecular Biology and Evolution, 2024 - academic.oup.com
Modern humans originated in Africa 300,000 yr ago, and before leaving their continent of
origin, they underwent a process of intense diversification involving complex demographic …

Archaic introgression contributed to shape the adaptive modulation of angiogenesis and cardiovascular traits in human high-altitude populations from the Himalayas

G Ferraretti, P Abondio, M Alberti, A Dezi, PT Sherpa… - Elife, 2024 - elifesciences.org
It is well established that several Homo sapiens populations experienced admixture with
extinct human species during their evolutionary history. Sometimes, such a gene flow could …

Whole genome sequencing of 76 Mexican Indigenous reveals recent selection signatures linked to pathogens and diet adaptation

F Miron-Toruno, E Morett, I Aguilar-Ordonez… - bioRxiv, 2024 - biorxiv.org
Whole genome scans for natural selection signatures across Mexican Indigenous (MI)
Populations remain underrepresented in the literature. Here, we conducted the first …