Associations of inferior frontal sulcal hyperintensities on brain MRI with cerebral small vessel disease, cognitive function, and depression symptoms

M Dörner, M Pfister, A Tyndall, R von Känel… - Scientific Reports, 2025 - nature.com
Inferior frontal sulcal hyperintensities (IFSH) observed on fluid-attenuated inversion recovery
(FLAIR) MRI have been proposed as indicators of elevated cerebrospinal fluid waste …

Cognitive reserve against Alzheimer's pathology is linked to brain activity during memory formation

N Vockert, J Machts, L Kleineidam, A Nemali… - Nature …, 2024 - nature.com
The cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain
function is disrupted by pathology associated with aging and neurodegeneration. Here, we …