Infectious and inflammatory pathways to cough
KF Naqvi, SB Mazzone… - Annual review of …, 2023 - annualreviews.org
Coughing is a dynamic physiological process resulting from input of vagal sensory neurons
innervating the airways and perceived airway irritation. Although cough serves to protect …
innervating the airways and perceived airway irritation. Although cough serves to protect …
The Fim and FhaB adhesins play a crucial role in nasal cavity infection and Bordetella pertussis transmission in a novel mouse catarrhal infection model
J Holubova, O Stanek, A Juhasz… - PLoS …, 2022 - journals.plos.org
Pulmonary infections caused by Bordetella pertussis used to be the prime cause of infant
mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in …
mortality in the pre-vaccine era and mouse models of pertussis pneumonia served in …
Intranasal challenge with B. pertussis leads to more severe disease manifestations in mice than aerosol challenge
KL Weaver, GJ Bitzer, MA Wolf, GM Pyles, MA DeJong… - Plos one, 2023 - journals.plos.org
The murine Bordetella pertussis challenge model has been utilized in preclinical research
for decades. Currently, inconsistent methodologies are employed by researchers across the …
for decades. Currently, inconsistent methodologies are employed by researchers across the …
Immunization with an mRNA DTP vaccine protects against pertussis in rats
GJ Bitzer, NA Fitzgerald, MA DeJong… - Infection and …, 2024 - journals.asm.org
Bordetella pertussis is a Gram-negative bacterium that is the causative agent of the
respiratory disease known as pertussis. Since the switch to the acellular vaccines of DTaP …
respiratory disease known as pertussis. Since the switch to the acellular vaccines of DTaP …
The mechanism of pertussis cough revealed by the mouse-coughing model
Y Hiramatsu, K Suzuki, T Nishida, N Onoda, T Satoh… - Mbio, 2022 - Am Soc Microbiol
Pertussis, also known as whoo** cough, is a contagious respiratory disease caused by
the Gram-negative bacterium Bordetella pertussis. This disease is characterized by severe …
the Gram-negative bacterium Bordetella pertussis. This disease is characterized by severe …
Multivalent mRNA-DTP vaccines are immunogenic and provide protection from Bordetella pertussis challenge in mice
Acellular multivalent vaccines for pertussis (DTaP and Tdap) prevent symptomatic disease
and infant mortality, but immunity to Bordetella pertussis infection wanes significantly over …
and infant mortality, but immunity to Bordetella pertussis infection wanes significantly over …
Long-Term Analysis of Pertussis Vaccine Immunity to Identify Potential Markers of Vaccine-Induced Memory Associated With Whole Cell But Not Acellular Pertussis …
Over two decades ago acellular pertussis vaccines (aP) replaced whole cell pertussis
vaccines (wP) in several countries. Since then, a resurgence in pertussis has been …
vaccines (wP) in several countries. Since then, a resurgence in pertussis has been …
Mucosal Vaccination with Live Attenuated Bordetella bronchiseptica Protects against Challenge in Wistar Rats
BM Chamorro, KD Luca, G Swaminathan… - Vaccines, 2023 - mdpi.com
Bordetella bronchiseptica (Bb) is a Gram-negative bacterium responsible for canine
infectious respiratory disease complex (CIRDC). Several vaccines targeting this pathogen …
infectious respiratory disease complex (CIRDC). Several vaccines targeting this pathogen …
Mucosal Immunization with DTaP Confers Protection against Bordetella pertussis Infection and Cough in Sprague-Dawley Rats
Pertussis is a respiratory disease caused by the Gram-negative pathogen, Bordetella
pertussis. The transition from a whole-cell pertussis vaccine (wP and DTP) to an acellular …
pertussis. The transition from a whole-cell pertussis vaccine (wP and DTP) to an acellular …
Current understanding of Bordetella‐induced cough
Y Horiguchi - Microbiology and Immunology, 2024 - Wiley Online Library
Typical pathogenic bacteria of the genus Bordetella cause respiratory diseases, many of
which are characterized by severe coughing in host animals. In human infections with these …
which are characterized by severe coughing in host animals. In human infections with these …