TFOS DEWS II diagnostic methodology report

JS Wolffsohn, R Arita, R Chalmers, A Djalilian… - The ocular …, 2017 - Elsevier
The role of the Tear Film and Ocular Surface Society (TFOS) Dry Eye Workshop (DEWS) II
Diagnostic Methodology Subcommittee was 1) to identify tests used to diagnose and monitor …

TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

Omics-driven systems interrogation of metabolic dysregulation in COVID-19 pathogenesis

JW Song, SM Lam, X Fan, WJ Cao, SY Wang, H Tian… - Cell metabolism, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic presents an unprecedented
threat to global public health. Herein, we utilized a combination of targeted and untargeted …

Dry eye disease associated with meibomian gland dysfunction: focus on tear film characteristics and the therapeutic landscape

JD Sheppard, KK Nichols - Ophthalmology and therapy, 2023 - Springer
Meibomian gland dysfunction (MGD) is highly prevalent and is the leading cause of
evaporative dry eye disease (DED). MGD is characterized by a reduction in meibum …

Integration of lipidomics and metabolomics for in-depth understanding of cellular mechanism and disease progression

R Wang, B Li, SM Lam, G Shui - Journal of Genetics and Genomics, 2020 - Elsevier
Mass spectrometry (MS)-based omics technologies are now widely used to profile small
molecules in multiple matrices to confer comprehensive snapshots of cellular metabolic …

[HTML][HTML] NOV03 for signs and symptoms of dry eye disease associated with meibomian gland dysfunction: the randomized phase 3 MOJAVE study

JD Sheppard, F Kurata, AT Epitropoulos… - American Journal of …, 2023 - Elsevier
Purpose To evaluate the efficacy and safety of NOV03 (perfluorohexyloctane) ophthalmic
drop for the treatment of signs and symptoms of dry eye disease (DED) associated with …

A review of structural and biomechanical changes in the cornea in aging, disease, and photochemical crosslinking

BJ Blackburn, MW Jenkins, AM Rollins… - … in bioengineering and …, 2019 - frontiersin.org
The study of corneal biomechanics is motivated by the tight relationship between
biomechanical properties and visual function within the ocular system. For instance …

Biochemistry of human tear film: A review

S Masoudi - Experimental eye research, 2022 - Elsevier
The precorneal tear film is a complex mixture of proteins, lipids, metabolites, and electrolytes
with different structures and functionalities. Sustainable production of each tear component …

BCLA CLEAR-Anatomy and physiology of the anterior eye

LE Downie, S Bandlitz, JPG Bergmanson… - Contact Lens and …, 2021 - Elsevier
A key element of contact lens practice involves clinical evaluation of anterior eye health,
including the cornea and limbus, conjunctiva and sclera, eyelids and eyelashes, lacrimal …

[HTML][HTML] Tissue adhesive hyaluronic acid hydrogels for sutureless stem cell delivery and regeneration of corneal epithelium and stroma

L Koivusalo, M Kauppila, S Samanta, VS Parihar… - Biomaterials, 2019 - Elsevier
Regeneration of a severely damaged cornea necessitates the delivery of both epithelium-
renewing limbal epithelial stem cells (LESCs) and stroma-repairing cells, such as human …