Recent publications have suggested that oxidative DNA damage mediated by hydroxyl
radical (˙ OH) is unimportant in vivo, and that carbonate anion radical (CO3˙−) plays the key …

This review surveys the major structural features in various groups of small molecules that
are considered to be antioxidants, including natural and synthetic compounds alike. Recent …

This article looks back to the antioxidant/free radical field in 1994 and discusses how it has
progressed in the past 18 years. In some areas, there has been little change: the role of …

The recent explosion of interest in the bioactivity of the the flavonoids of higher plants is due,
at least in part, to the potential health benefits of these polyphenolic components of major …

Publisher Summary This chapter discusses the role of free radicals and catalytic metal ions
in human disease. The importance of transition metal ions in mediating oxidant damage …

The free radical scavenging activity and reducing power of 16 phenolic compounds
including four hydroxycinnamic acid derivatives namely ferulic acid, caffeic acid, sinapic acid …

Free radicals and other reactive species (RS) are thought to play an important role in many
human diseases. Establishing their precise role requires the ability to measure them and the …

When life first evolved on Earth, there was little oxygen in the atmosphere. Evolution of
antioxidant defences must have been closely associated with the evolution of …

An antioxidant is a substance that, when present at low concentrations compared to those of
an oxidizable substrate, significantly delays or prevents oxidation of that substrate. Many …

1. Lipoic acid is an example of an existing drug whose therapeutic effect has been related to
its antioxidant activity. 2. 2. Antioxidant activity is a relative concept: it depends on the kind of …