EAU-EANM-ESTRO-ESUR-SIOG guidelines on prostate cancer. Part II—2020 update: treatment of relapsing and metastatic prostate cancer

P Cornford, RCN van den Bergh, E Briers… - European urology, 2021 - Elsevier
Objective To present a summary of the 2020 version of the European Association of Urology
(EAU)-European Association of Nuclear Medicine (EANM)-European Society for …

Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Survival with olaparib in metastatic castration-resistant prostate cancer

M Hussain, J Mateo, K Fizazi, F Saad… - … England Journal of …, 2020 - Mass Medical Soc
Background We previously reported that olaparib led to significantly longer imaging-based
progression-free survival than the physician's choice of enzalutamide or abiraterone among …

NCCN guidelines insights: Prostate cancer, version 1.2021: Featured updates to the NCCN guidelines

E Schaeffer, S Srinivas, ES Antonarakis… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Prostate Cancer address staging and risk assessment after a
prostate cancer diagnosis and include management options for localized, regional, and …

Nivolumab plus ipilimumab for metastatic castration-resistant prostate cancer: preliminary analysis of patients in the CheckMate 650 trial

P Sharma, RK Pachynski, V Narayan, A Fléchon… - Cancer cell, 2020 - cell.com
Metastatic castration-resistant prostate cancer (mCRPC) is immunologically" cold" and
predominantly resistant to immune checkpoint therapy due to few tumor-infiltrating T cells …

[HTML][HTML] Management of patients with advanced prostate cancer: report of the advanced prostate cancer consensus conference 2019

S Gillessen, G Attard, TM Beer, H Beltran, A Bjartell… - European urology, 2020 - Elsevier
Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but there are still many aspects of management …

[177Lu] Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer (TheraP): a randomised, open-label, phase 2 trial

MS Hofman, L Emmett, S Sandhu, A Iravani… - The Lancet, 2021 - thelancet.com
Summary Background Lutetium-177 [177 Lu] Lu-PSMA-617 is a radiolabelled small
molecule that delivers β radiation to cells expressing prostate-specific membrane antigen …

Prostate cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

C Parker, E Castro, K Fizazi, A Heidenreich… - Annals of …, 2020 - annalsofoncology.org
Subclinical prostate cancer is common in men> 50 years. Population-based screening of
men aged between 55 and 69 years, using prostate-specific antigen (PSA) testing, has been …

Genomic analysis of circulating tumor DNA in 3,334 patients with advanced prostate cancer identifies targetable BRCA alterations and AR resistance mechanisms

H Tukachinsky, RW Madison, JH Chung… - Clinical Cancer …, 2021 - AACR
Purpose: Comprehensive genomic profiling (CGP) is of increasing value for patients with
metastatic castration-resistant prostate cancer (mCRPC). mCRPC tends to metastasize to …

Advanced prostate cancer: treatment advances and future directions

U Swami, TR McFarland, R Nussenzveig, N Agarwal - Trends in cancer, 2020 - cell.com
Prostate cancer affects one in every nine men in the USA and is the second leading cause of
cancer-related death. The treatment landscape of advanced prostate cancer is changing …