Recent biological applications of heterocyclic hybrids containing s-triazine scaffold

MI Ali, MM Naseer - RSC advances, 2023 - pubs.rsc.org
s-Triazine possesses an auspicious status in the field of drug discovery and development
owing to its presence in many naturally occurring compounds as well as commercially …

Synthesis of thiazolidine-2, 4-dione tethered 1, 2, 3-triazoles as α-amylase inhibitors: in vitro approach coupled with QSAR, molecular docking, molecular dynamics …

R Singh, J Sindhu, M Devi, P Kumar, S Lal… - European Journal of …, 2024 - Elsevier
A new series of thiazolidine-2, 4-dione tethered 1, 2, 3-triazole derivatives were designed,
synthesized and screened for their α-amylase inhibitory potential employing in vitro and in …

Sustainable click reactions: Use of greener reaction media in the synthesis of 1, 2, 3-triazoles

LA Martinho, CKZ Andrade - Tetrahedron, 2024 - Elsevier
Heterocyclic compounds are widely found in nature, more specifically, five-or six-membered
rings nitrogen heterocycles are important in the synthesis of biologically active compounds …

Investigation of solvatochromic, optical, organic field effect transistor (OFET), antibacterial, and molecular bonding of some azothiazolidine-2, 4-dione (AZO-TZD) dyes

HY Nyaki, NO Mahmoodi, HT Nahzomi - Journal of Photochemistry and …, 2024 - Elsevier
Here, new AZO-TZD derivatives (1− 11) were synthesized using cellulose sulphuric acid
(CSA) as a catalyst to prepare diazonium salts and Knoevenagel condensation to produce …

Synthesis, Biological Evaluation, and Molecular Docking Investigation of New Series of Azoimino-Sulfathiazole (AIST) Derivatives

NO Mahmoodi, F Amouee… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Sulfonamides are important compounds with special applications in pharmaceuticals due to
their antibacterial and antiparasitic properties, and they are known as sulfa drugs (SDs). In …

Flexible green synthesis of 2-benzyl-3‑hydroxy-1H-pyrazolo ([1, 2-b] phthalazine and [1, 2-a] pyridazine)‑dione derivatives using CuI@ KSF nanocatalyst under …

NO Mahmoodi, A Shahabbasi, HY Nyaki… - Journal of Molecular …, 2025 - Elsevier
In the frame of research that examines the use of task CuI@ KSF nanoparticles as an
efficient catalyst, new 1H-pyrazolo [1, 2-b] phthalazine-5, 10‑dione (HPPhD) and 1H …

Synthesis, biological evaluation and molecular dynamics simulations of new sulfonylurea derivatives bearing biphenyl moieties as potential NLRP3 inhibitors

X **ong, R Zhang, Z Min, J Liu, P Zheng, X Li… - Research on Chemical …, 2024 - Springer
Here in this work we designed and synthesized a series of new sulfonylurea derivatives
bearing biphenyl moieties whose structures were confirmed by 1H-NMR, 13C-NMR, IR and …

Synthesis, Characterization, Molecular Docking, and Investigation of Antibacterial Properties of New Derivatives of 1‐H‐Phenanthro [9,10‐d] Imidazole

NO Mahmoodi, A Rajabi, HY Nyaki… - Chemistry & …, 2024 - Wiley Online Library
In this study, several imidazole derivatives in one pot multicomponent reaction from various
aldehydes 1 (a–z), 9, 10‐phenanthrenequinone, or benzyl (2), and ammonium acetate (3) …

A Flexible Green Synthesis of New 1h-Pyrazolo ([1, 2-B] or [1, 2-A]) Phthalazine or Pyridazine-Trione Derivatives with Cui@ Ksf Nanocatalyst Under Solvent Free …

N Mahmoodi, A Shahabbasi, HY Nyaki… - Available at SSRN … - papers.ssrn.com
In the frame of research that examines the, use of task CuI@ KSF nanoparticles as an
efficient catalyst have been for the preparation of 1H-pyrazolo ([1, 2-b] or [1, 2-a]) …