Gut reactions: breaking down xenobiotic–microbiome interactions

G Clarke, KV Sandhu, BT Griffin, TG Dinan… - Pharmacological …, 2019 - Elsevier
The microbiome plays a key role in health and disease, and there has been considerable
interest in therapeutic targeting of the microbiome as well as mining this rich resource in …

[HTML][HTML] Circulating microRNAs as potential biomarkers for psychiatric and neurodegenerative disorders

MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids
such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …

Roles of PI3K/AKT/GSK3 pathway involved in psychiatric illnesses

S Matsuda, Y Ikeda, M Murakami, Y Nakagawa, A Tsuji… - Diseases, 2019 - mdpi.com
Psychiatric illnesses may be qualified to the cellular impairments of the function for survival
or death in neurons, which may consequently appear as abnormalities in the neuroplasticity …

CircDYM ameliorates depressive-like behavior by targeting miR-9 to regulate microglial activation via HSP90 ubiquitination

Y Zhang, L Du, Y Bai, B Han, C He, L Gong… - Molecular …, 2020 - nature.com
Circular RNAs (circRNAs), highly expressed in the central nervous system, are involved in
various regulatory processes and implicated in some pathophysiology. However, the …

Blood-based biomarkers of antidepressant response to ketamine and esketamine: A systematic review and meta-analysis

GC Medeiros, TD Gould, WL Prueitt, J Nanavati… - Molecular …, 2022 - nature.com
Abstract (R, S)-ketamine (ketamine) and its enantiomer (S)-ketamine (esketamine) can
produce rapid and substantial antidepressant effects. However, individual response to …

MicroRNAs and exosomes in depression: potential diagnostic biomarkers

J Tavakolizadeh, K Roshanaei… - Journal of Cellular …, 2018 - Wiley Online Library
Depression is known as one of important psychiatric disorders which could be associated
with disability among various populations. Diagnostic and statistical manual of mental …

Genome-wide, integrative analysis implicates exosome-derived microRNA dysregulation in schizophrenia

Y Du, Y Yu, Y Hu, XW Li, ZX Wei, RY Pan… - Schizophrenia …, 2019 - academic.oup.com
Genetic variants conferring risk for schizophrenia (SCZ) have been extensively studied, but
the role of posttranscriptional mechanisms in SCZ is not well studied. Here we performed the …

Exploiting circulating MicroRNAs as biomarkers in psychiatric disorders

B Roy, Y Yoshino, L Allen, K Prall, G Schell… - Molecular diagnosis & …, 2020 - Springer
Non-invasive peripheral biomarkers play a significant role in both disease diagnosis and
progression. In the past few years, microRNA (miRNA) expression changes in circulating …

Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression

L Kaurani, M Besse, I Methfessel, A Methi… - Translational …, 2023 - nature.com
There is a strong medical need to develop suitable biomarkers to improve the diagnosis and
treatment of depression, particularly in predicting response to certain therapeutic …

Non-coding RNAs in depression: Promising diagnostic and therapeutic biomarkers

Y Shi, Q Wang, R Song, Y Kong, Z Zhang - EBioMedicine, 2021 - thelancet.com
Abstract Non-coding RNAs (ncRNAs), including microRNAs, circular RNAs, and long non-
coding RNAs, are important regulators of normal biological processes and their abnormal …