Nanomedicine tumor targeting

T Lammers - Advanced Materials, 2024 - Wiley Online Library
Nanomedicines are extensively explored for cancer therapy. By delivering drug molecules
more efficiently to pathological sites and by attenuating their accumulation in healthy organs …

The spatiotemporal journey of nanomedicines in solid tumors on their therapeutic efficacy

M Qin, H **a, W Xu, B Chen, Y Wang - Advanced Drug Delivery Reviews, 2023 - Elsevier
The rapid development of nanomedicines is revolutionizing the landscape of cancer
treatment, while effectively delivering them into solid tumors remains a formidable challenge …

Engineering kinetics of TLR7/8 agonist release from bottlebrush prodrugs enables tumor-focused immune stimulation

SH Bhagchandani, F Vohidov, LE Milling, EY Tong… - Science …, 2023 - science.org
Imidazoquinolines (IMDs), such as resiquimod (R848), are of great interest as potential
cancer immunotherapies because of their ability to activate Toll-like receptor 7 (TLR7) …

Hypoxia-responsive host–guest drug delivery system

XY Hu, R Fu, DS Guo - Accounts of Materials Research, 2023 - ACS Publications
Conspectus A host–guest drug delivery system (HGDDS) refers to a host–guest complex of
an artificial receptor and a therapeutic agent which can dissociate at the lesion site and …

In Situ Orthogonal Polymerization for Constructing Fast-Charging and Long-Lifespan Li Metal Batteries with Topological Copolymer Electrolytes

K Guo, S Li, J Wang, Z Shi, Y Wang, Z Xue - ACS Energy Letters, 2024 - ACS Publications
Fast-charging Li metal batteries (LMBs) with low cost, high safety, and long lifespan are
highly desirable for next-generation energy storage technologies yet have been rarely …

A Photoactivatable Self-Assembled Nanoagonist for Synergistic Therapy against Pancreatic Ductal Adenocarcinoma

X Xu, T Li, T Yang, F Liu, Z Guo, H Wu, Y Tang… - Nano Letters, 2024 - ACS Publications
Immunotherapy has revolutionized the cancer treatment paradigm, yet efficient
immunotherapeutic responses against immune-cold/desert cancers remain challenging …

Thiol-triggered deconstruction of bifunctional silyl ether terpolymers via an SN Ar-triggered cascade

CM Brown, KEL Husted, Y Wang, LJ Kilgallon… - Chemical …, 2023 - pubs.rsc.org
While Si-containing polymers can often be deconstructed using chemical triggers such as
fluoride, acids, and bases, they are resistant to cleavage by mild reagents such as biological …

Cyclic vs Linear Bottlebrush Polymers in Solution: Side-Chain Length Effect

G Chen, EE Dormidontova - Macromolecules, 2023 - ACS Publications
Bottlebrush polymers (BBPs) of different architecture are of considerable interest for a broad
range of applications, including nanomedicine, electronics, and self-healing materials …

Advances in Injectable Polymeric Biomaterials and Their Contemporary Medical Practices

S Beilharz, MK Debnath, D Vinella… - ACS Applied Bio …, 2024 - ACS Publications
Injectable biomaterials have been engineered to operate within the human body, offering
versatile solutions for minimally invasive therapies and meeting several stringent …

Space station-like composite nanoparticles for co-delivery of multiple natural compounds from chinese medicine and hydrogen in combating sensorineural hearing …

W **ao, K He, C Yu, Z Zhou, L **a, S **e… - Molecular …, 2023 - ACS Publications
Ototoxic drugs such as aminoglycoside antibiotics and cisplatin (CDDP) can cause
sensorineural hearing loss (SNHL), which is closely related to oxidative stress and the …