The structure of the nuclear pore complex (an update)
The nuclear pore complex (NPC) serves as the sole bidirectional gateway of
macromolecules in and out of the nucleus. Owing to its size and complexity (∼ 1,000 protein …
macromolecules in and out of the nucleus. Owing to its size and complexity (∼ 1,000 protein …
The nuclear pore complex: understanding its function through structural insight
Nuclear pore complexes (NPCs) fuse the inner and outer nuclear membranes to form
channels across the nuclear envelope. They are large macromolecular assemblies with a …
channels across the nuclear envelope. They are large macromolecular assemblies with a …
AI-based structure prediction empowers integrative structural analysis of human nuclear pores
INTRODUCTION The eukaryotic nucleus protects the genome and is enclosed by the two
membranes of the nuclear envelope. Nuclear pore complexes (NPCs) perforate the nuclear …
membranes of the nuclear envelope. Nuclear pore complexes (NPCs) perforate the nuclear …
Architecture of the cytoplasmic face of the nuclear pore
INTRODUCTION Cytoplasmic face of the human NPC. Near-atomic composite structure of
the NPC generated by docking high-resolution crystal structures into a cryo‑ET …
the NPC generated by docking high-resolution crystal structures into a cryo‑ET …
[HTML][HTML] Comprehensive structure and functional adaptations of the yeast nuclear pore complex
Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of
macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner …
macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner …
Structure and assembly of the nuclear pore complex
B Hampoelz, A Andres-Pons… - Annual review of …, 2019 - annualreviews.org
Nuclear pore complexes (NPCs) mediate nucleocytoplasmic exchange. They are
exceptionally large protein complexes that fuse the inner and outer nuclear membranes to …
exceptionally large protein complexes that fuse the inner and outer nuclear membranes to …
The nuclear pore complex as a flexible and dynamic gate
Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary
transport gates for molecular exchange between nucleus and cytoplasm. Strip** the …
transport gates for molecular exchange between nucleus and cytoplasm. Strip** the …
Probing nuclear pore complex architecture with proximity-dependent biotinylation
Proximity-dependent biotin identification (BioID) is a method for identifying protein
associations that occur in vivo. By fusing a promiscuous biotin ligase to a protein of interest …
associations that occur in vivo. By fusing a promiscuous biotin ligase to a protein of interest …
Architecture of the linker-scaffold in the nuclear pore
INTRODUCTION In eukaryotic cells, the selective bidirectional transport of macromolecules
between the nucleus and cytoplasm occurs through the nuclear pore complex (NPC) …
between the nucleus and cytoplasm occurs through the nuclear pore complex (NPC) …
Molecular architecture of the inner ring scaffold of the human nuclear pore complex
Nuclear pore complexes (NPCs) are 110-megadalton assemblies that mediate
nucleocytoplasmic transport. NPCs are built from multiple copies of~ 30 different …
nucleocytoplasmic transport. NPCs are built from multiple copies of~ 30 different …