Structural parameters of nanoparticles affecting their toxicity for biomedical applications: a review

R Abbasi, G Shineh, M Mobaraki, S Doughty… - Journal of Nanoparticle …, 2023 - Springer
Rapidly growing interest in using nanoparticles (NPs) for biomedical applications has
increased concerns about their safety and toxicity. In comparison with bulk materials, NPs …

Tumor abnormality-oriented nanomedicine design

Q Zhou, J **ang, N Qiu, Y Wang, Y Piao, S Shao… - Chemical …, 2023 - ACS Publications
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Polymeric delivery of therapeutic nucleic acids

R Kumar, CF Santa Chalarca, MR Bockman… - Chemical …, 2021 - ACS Publications
The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Concepts of nanoparticle cellular uptake, intracellular trafficking, and kinetics in nanomedicine

ND Donahue, H Acar, S Wilhelm - Advanced drug delivery reviews, 2019 - Elsevier
Nanoparticle-based therapeutics and diagnostics are commonly referred to as
nanomedicine and may significantly impact the future of healthcare. However, the clinical …

[HTML][HTML] Cellular uptake and retention of nanoparticles: Insights on particle properties and interaction with cellular components

R Augustine, A Hasan, R Primavera, RJ Wilson… - Materials Today …, 2020 - Elsevier
The utilization of nanomaterials in the biological and medical field is quickly progressing,
particularly in areas where traditional diagnostics and treatment approaches have limited …

Thermally activated delayed fluorescence material: an emerging class of metal‐free luminophores for biomedical applications

F Fang, L Zhu, M Li, Y Song, M Sun, D Zhao… - Advanced …, 2021 - Wiley Online Library
The development of simple, efficient, and biocompatible organic luminescent molecules is of
great significance to the clinical transformation of biomaterials. In recent years, purely …

Synthesis, structure, properties, and applications of bimetallic nanoparticles of noble metals

K Loza, M Heggen, M Epple - Advanced functional materials, 2020 - Wiley Online Library
Bimetallic nanoparticles of noble metals are of high interest in imaging, biomedical devices,
including nanomedicine, and heterogeneous catalysis. Synthesis, properties …

Progress, challenges, and future of nanomedicine

C Zhang, L Yan, X Wang, S Zhu, C Chen, Z Gu, Y Zhao - Nano Today, 2020 - Elsevier
Nanotherapeutics exhibit unique advantages in clinical outcomes compared with
conventional small molecular drugs. The past three decades have seen intensive research …

Ultrasound‐controlled drug release and drug activation for cancer therapy

L Tu, Z Liao, Z Luo, YL Wu, A Herrmann, S Huo - Exploration, 2021 - Wiley Online Library
Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …