Hepatic injury and subsequent hepatic failure due to both intentional and non-intentional
overdose of acetaminophen (APAP) has affected patients for decades, and involves the …

Acetaminophen (APAP) is a safe and effective analgesic and antipyretic. 1 It is widely
available as a single-component medication and also as a component of a plethora of …

Acetaminophen overdose is a common reason for hospital admission and the most frequent
cause of hepatotoxicity in the Western world. Early identification would facilitate patient …

Acetaminophen (APAP or paracetamol or N-acetyl-p-aminophenol), a safe and effective
antipyretic and analgesic, has been extensively used around the world since 1955. It is …

Background Paracetamol (acetaminophen) is the most widely used non‐prescription
analgesic in the world. Paracetamol is commonly taken in overdose either deliberately or …

Drug induced liver injury (DILI) is a common cause of acute liver injury. Paracetamol, also
known as acetaminophen, is a widely used anti-pyretic that has long been established to …

Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at
therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The …

A 25-year-old man presents to the emergency department with a toothache and is found to
have been ingesting large quantities of acetaminophen. Although no acetaminophen is …

Oxidative stress is a key pathological feature implicated in both acute and chronic liver
diseases, including drug‐induced liver injury (DILI). The latter describes hepatic injury …

Background Paracetamol poisoning is common worldwide. It is treated with intravenous
acetylcysteine, but the standard regimen is complex and associated with frequent adverse …