The skin is essential for survival and protects our body against biological attacks, physical
stress, chemical injury, water loss, ultraviolet radiation and immunological impairment. The …

Aliment Pharmacol Ther 2011; 34: 146–165 Summary Background Factors other than acid
may play a role in gastro‐oesophageal reflux disease (GERD) and its complications. Aim To …

Gastroesophageal reflux is associated with adenocarcinoma in Barrett's esophagus, but the
incidence of this tumor is rising, despite widespread use of acid-suppressing medications …

Cervical cancer originates with human papillomavirus (HPV) infection and progresses via
histologically defined premalignant stages. Here we compare normal cervical epithelium …

Deoxycholic acid (DCA) is a secondary bile acid implicated in various cancers of the
gastrointestinal (GI) tract. In oesophageal adenocarcinoma, DCA is believed to contribute to …

Basal progenitor cells are crucial for maintaining foregut (the esophagus and forestomach)
homeostasis. When their function is dysregulated, it can promote inflammation and …

By using cDNA microarray analysis, we identified cornulin (CRNN) gene was frequently
downregulated in esophageal squamous cell carcinoma (ESCC). In the present study, we …

Thyroid nodules are common in the general population and vary widely in their propensity to
harbor thyroid malignancies. The category of follicular lesion of undetermined significance …

Early events in the development of esophageal squamous cell carcinoma (ESCC) are poorly
understood and many of the key molecules involved have not yet been identified. We …

Anterior gradient-2 protein was identified using proteomic technologies as a p53 inhibitor
which is overexpressed in human cancers, and this protein presents a novel pro-oncogenic …