Discovery of 2-(4-(2-fluoroethoxy) piperidin-1-yl)-9-methyl-9H-pyrrolo [2, 3-b: 4, 5-c'] dipyridine ([18F] PI-2014) as PET tracer for the detection of pathological …
E Gabellieri, F Capotosti, J Molette… - European journal of …, 2020 - Elsevier
The compound screening was initiated with a direct staining assay to identify compounds
binding to Tau aggregates and not Abeta plaques using human brain sections derived from …
binding to Tau aggregates and not Abeta plaques using human brain sections derived from …
Exploring the Propensities of Fluorescent Carbazole Analogs toward the Inhibition of Amyloid Aggregation in Type 2 Diabetes: An Experimental and Theoretical …
Amyloid aggregation is a pathological trait observed in many incurable and fatal
neurodegenerative and metabolic diseases associated with misfolding and self-assembly of …
neurodegenerative and metabolic diseases associated with misfolding and self-assembly of …
9H-pyrrolo-dipyridine derivatives
J Mercier, L Provins, C Vermeiren… - US Patent 11,312,716, 2022 - Google Patents
US11312716B2 - 9H-pyrrolo-dipyridine derivatives - Google Patents US11312716B2 - 9H-pyrrolo-dipyridine
derivatives - Google Patents 9H-pyrrolo-dipyridine derivatives Download PDF Info …
derivatives - Google Patents 9H-pyrrolo-dipyridine derivatives Download PDF Info …
Azaindole compounds as histone methyltransferase inhibitors
C Yu, M Yu, M Zancanella, Z Li - US Patent 11,111,243, 2021 - Google Patents
The present disclosure provides certain angular tricyclic compounds that are histone
methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of …
methyltransferases G9a and/or GLP inhibitors and are therefore useful for the treatment of …