[HTML][HTML] Mechanics in the nervous system: From development to disease

EK Pillai, K Franze - Neuron, 2024 - cell.com
Physical forces are ubiquitous in biological processes across scales and diverse contexts.
This review highlights the significance of mechanical forces in nervous system development …

Brain aging mechanisms with mechanical manifestations

Y Blinkouskaya, A Caçoilo, T Gollamudi… - Mechanisms of ageing …, 2021 - Elsevier
Brain aging is a complex process that affects everything from the subcellular to the organ
level, begins early in life, and accelerates with age. Morphologically, brain aging is primarily …

Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging

I Sack - Nature Reviews Physics, 2023 - nature.com
Magnetic resonance elastography (MRE) is a versatile imaging technique for map** the
viscoelastic properties of soft biological tissues. It has been widely used to detect liver …

Tissue mechanics regulate brain development, homeostasis and disease

JM Barnes, L Przybyla, VM Weaver - Journal of cell science, 2017 - journals.biologists.com
All cells sense and integrate mechanical and biochemical cues from their environment to
orchestrate organismal development and maintain tissue homeostasis …

The mechanobiology of brain function

WJ Tyler - Nature Reviews Neuroscience, 2012 - nature.com
All cells are influenced by mechanical forces. In the brain, force-generating and load-
bearing proteins twist, turn, ratchet, flex, compress, expand and bend to mediate neuronal …

Magnetic resonance elastography (MRE) of the human brain: technique, findings and clinical applications

LV Hiscox, CL Johnson, E Barnhill… - Physics in Medicine …, 2016 - iopscience.iop.org
Neurological disorders are one of the most important public health concerns in developed
countries. Established brain imaging techniques such as magnetic resonance imaging (MRI) …

Tuning immunity through tissue mechanotransduction

H Du, JM Bartleson, S Butenko, V Alonso… - Nature Reviews …, 2023 - nature.com
Immune responses are governed by signals from the tissue microenvironment, and in
addition to biochemical signals, mechanical cues and forces arising from the tissue, its …

MR elastography of the brain and its application in neurological diseases

MC Murphy, J Huston III, RL Ehman - Neuroimage, 2019 - Elsevier
Magnetic resonance elastography (MRE) is an imaging technique for noninvasively and
quantitatively assessing tissue stiffness, akin to palpation. MRE is further able assess the …

[HTML][HTML] Measuring the effects of aging and sex on regional brain stiffness with MR elastography in healthy older adults

A Arani, MC Murphy, KJ Glaser, A Manduca, DS Lake… - Neuroimage, 2015 - Elsevier
Abstract Changes in tissue composition and cellular architecture have been associated with
neurological disease, and these in turn can affect biomechanical properties. Natural …

[HTML][HTML] Regional brain stiffness changes across the Alzheimer's disease spectrum

MC Murphy, DT Jones, CR Jack Jr, KJ Glaser… - NeuroImage: Clinical, 2016 - Elsevier
Magnetic resonance elastography (MRE) is an MRI-based technique to noninvasively
measure tissue stiffness. Currently well established for clinical use in the liver, MRE is …