Recruitment of RNA polymerase III to its target promoters
L Schramm, N Hernandez - Genes & development, 2002 - genesdev.cshlp.org
A key step in retrieving the information stored in the complex genomes of eukaryotes
involves the identification of transcription units and, more specifically, the recognition of …
involves the identification of transcription units and, more specifically, the recognition of …
Dysregulation of the basal RNA polymerase transcription apparatus in cancer
Mutations that directly affect transcription by RNA polymerases rank among the most central
mediators of malignant transformation, but the frequency of new anticancer drugs that …
mediators of malignant transformation, but the frequency of new anticancer drugs that …
The Genome of the Kinetoplastid Parasite, Leishmania major
Leishmania species cause a spectrum of human diseases in tropical and subtropical
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
regions of the world. We have sequenced the 36 chromosomes of the 32.8-megabase …
[LIBRO][B] Nucleic acids in chemistry and biology
GM Blackburn - 2006 - books.google.com
The structure, function and reactions of nucleic acids are central to molecular biology and
are crucial for the understanding of complex biological processes involved. Revised and …
are crucial for the understanding of complex biological processes involved. Revised and …
Digital logic circuits in yeast with CRISPR-dCas9 NOR gates
Natural genetic circuits enable cells to make sophisticated digital decisions. Building equally
complex synthetic circuits in eukaryotes remains difficult, however, because commonly used …
complex synthetic circuits in eukaryotes remains difficult, however, because commonly used …
Identification of cis-acting sites for condensin loading onto budding yeast chromosomes
C D'Ambrosio, CK Schmidt, Y Katou… - Genes & …, 2008 - genesdev.cshlp.org
Eukaryotic chromosomes reach their stable rod-shaped appearance in mitosis in a reaction
dependent on the evolutionarily conserved condensin complex. Little is known about how …
dependent on the evolutionarily conserved condensin complex. Little is known about how …
Efficient genome editing using tRNA promoter-driven CRISPR/Cas9 gRNA in Aspergillus niger
L Song, JP Ouedraogo, M Kolbusz, TTM Nguyen… - PloS one, 2018 - journals.plos.org
As a powerful tool for fast and precise genome editing, the CRISPR/Cas9 system has been
applied in filamentous fungi to improve the efficiency of genome alteration. However, the …
applied in filamentous fungi to improve the efficiency of genome alteration. However, the …
mTOR associates with TFIIIC, is found at tRNA and 5S rRNA genes, and targets their repressor Maf1
T Kantidakis, BA Ramsbottom… - Proceedings of the …, 2010 - National Acad Sciences
Synthesis of tRNA and 5S rRNA by RNA polymerase (pol) III is regulated by the mTOR
pathway in mammalian cells. The mTOR kinase localizes to tRNA and 5S rRNA genes …
pathway in mammalian cells. The mTOR kinase localizes to tRNA and 5S rRNA genes …
A role for TFIIIC transcription factor complex in genome organization
K Noma, HP Cam, RJ Maraia, SIS Grewal - Cell, 2006 - cell.com
Eukaryotic genome complexity necessitates boundary and insulator elements to partition
genomic content into distinct domains. We show that inverted repeat (IR) boundary elements …
genomic content into distinct domains. We show that inverted repeat (IR) boundary elements …
Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription
R Upadhya, JH Lee, IM Willis - Molecular cell, 2002 - cell.com
Maf1 is a putative repressor of RNA polymerase (pol) III transcription that is conserved from
yeast to humans. Here we show that Maf1 is a common component of multiple signaling …
yeast to humans. Here we show that Maf1 is a common component of multiple signaling …