[HTML][HTML] Glucagon-like peptide-1 (GLP-1) receptor agonists and neuroinflammation: Implications for neurodegenerative disease treatment

KO Kopp, EJ Glotfelty, Y Li, NH Greig - Pharmacological research, 2022‏ - Elsevier
Chronic, excessive neuroinflammation is a key feature of neurodegenerative diseases such
as Alzheimer's disease (AD) and Parkinson's disease (PD). However, neuroinflammatory …

Current and future treatments in Alzheimer disease: an update

KG Yiannopoulou… - Journal of central …, 2020‏ - journals.sagepub.com
Disease-modifying treatment strategies for Alzheimer disease (AD) are still under extensive
research. Nowadays, only symptomatic treatments exist for this disease, all trying to …

Ubiquitin signalling in neurodegeneration: mechanisms and therapeutic opportunities

MF Schmidt, ZY Gan, D Komander… - Cell Death & …, 2021‏ - nature.com
Neurodegenerative diseases are characterised by progressive damage to the nervous
system including the selective loss of vulnerable populations of neurons leading to motor …

Piper Species: A Comprehensive Review on Their Phytochemistry, Biological Activities and Applications

B Salehi, ZA Zakaria, R Gyawali, SA Ibrahim… - Molecules, 2019‏ - mdpi.com
Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

[HTML][HTML] The potential mechanism of postoperative cognitive dysfunction in older people

X Lin, Y Chen, P Zhang, G Chen, Y Zhou, X Yu - Experimental gerontology, 2020‏ - Elsevier
Postoperative cognitive dysfunction (POCD) is a common disorder following surgery, which
seriously threatens the quality of patients' life, especially the older people. Accumulating …

Neuropharmacological effects of quercetin: a literature-based review

MS Islam, C Quispe, R Hossain, MT Islam… - Frontiers in …, 2021‏ - frontiersin.org
Quercetin (QUR) is a natural bioactive flavonoid that has been lately very studied for its
beneficial properties in many pathologies. Its neuroprotective effects have been …

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease

A Boza-Serrano, R Ruiz, R Sanchez-Varo… - Acta …, 2019‏ - Springer
Alzheimer's disease (AD) is a progressive neurodegenerative disease in which the
formation of extracellular aggregates of amyloid beta (Aβ) peptide, fibrillary tangles of …

[HTML][HTML] A critical review on quercetin bioflavonoid and its derivatives: scope, synthesis, and biological applications with future prospects

S Dhanaraj - Arabian Journal of Chemistry, 2023‏ - Elsevier
Lifestyle is an important factor in health, and researchers are trying to see the adverse effect
on human health of a change in lifestyle. Many people follow unhealthy lifestyles, which …

Targeting neuroinflammation in Alzheimer's disease

MR Bronzuoli, A Iacomino, L Steardo… - Journal of inflammation …, 2016‏ - Taylor & Francis
Almost 47 million people suffer from dementia worldwide, with an estimated new case
diagnosed every 3.2 seconds. Alzheimer's disease (AD) accounts for approximately 60 …

[HTML][HTML] Peptides as therapeutic agents for inflammatory-related diseases

S La Manna, C Di Natale, D Florio… - International journal of …, 2018‏ - mdpi.com
Inflammation is a physiological mechanism used by organisms to defend themselves
against infection, restoring homeostasis in damaged tissues. It represents the starting point …