New frontiers and develo** applications in 19F NMR
1.2. Background Fluorine NMR offers many attractive features, most notably detection
sensitivity approaching that of protons. 19 F has a nuclear spin I= 1/2, a gyromagnetic ratio …
sensitivity approaching that of protons. 19 F has a nuclear spin I= 1/2, a gyromagnetic ratio …
Labeling cells for in vivo tracking using 19F MRI
Noninvasive in vivo cell tracking is crucial to fully understand the function of mobile and/or
transplanted cells, particularly immune cells and cellular therapeutics. 19F MRI for cell …
transplanted cells, particularly immune cells and cellular therapeutics. 19F MRI for cell …
Comparison of different compressed sensing algorithms for low SNR 19F MRI applications—Imaging of transplanted pancreatic islets and cells labeled with …
Transplantation of pancreatic islets is a possible treatment option for patients suffering from
Type I diabetes. In vivo imaging of transplanted islets is important for assessment of the …
Type I diabetes. In vivo imaging of transplanted islets is important for assessment of the …
Indomethacin treatment prevents high fat diet-induced obesity and insulin resistance but not glucose intolerance in C57BL/6J mice
Chronic low grade inflammation is closely linked to obesity-associated insulin resistance. To
examine how administration of the anti-inflammatory compound indomethacin, a general …
examine how administration of the anti-inflammatory compound indomethacin, a general …
Adaptive changes of human islets to an obesogenic environment in the mouse
S Gargani, J Thévenet, JE Yuan, B Lefebvre… - Diabetologia, 2013 - Springer
Aims/hypothesis In this study, we used an immunodeficient mouse model to explore, in vivo,
the longitudinal adaptation of human islets to an obesogenic environment. Methods Non …
the longitudinal adaptation of human islets to an obesogenic environment. Methods Non …
Design and evaluation of theranostic perfluorocarbon particles for simultaneous antigen-loading and 19F-MRI tracking of dendritic cells
H Dewitte, B Geers, S Liang, U Himmelreich… - Journal of Controlled …, 2013 - Elsevier
Perfluorocarbon (PFC) particles are currently on the rise as cell labeling agents for 19F-MRI
tracking of dendritic cell (DC)-based vaccines. In this work, we design theranostic PFC …
tracking of dendritic cell (DC)-based vaccines. In this work, we design theranostic PFC …
In vivo 19-fluorine magnetic resonance imaging
The 19 F nucleus has a complex role in vivo, particularly when it comes to in vivo imaging
applications—ironically, endogenous fluorine is nearly invisible to imaging techniques …
applications—ironically, endogenous fluorine is nearly invisible to imaging techniques …
Synthesis, Derivatization, and Structural Analysis of Phosphorylated Mono-, Di-, and Trifluorinated d-Gluco-heptuloses by Glucokinase: Tunable …
JS Zhu, KM Stiers, SM Winter, AD Garcia, AF Versini… - ACS …, 2019 - ACS Publications
Glucokinase phosphorylated a series of C-1 fluorinated α-d-gluco-heptuloses. These
phosphorylated products were discovered to be inhibitors of α-phosphomannomutase …
phosphorylated products were discovered to be inhibitors of α-phosphomannomutase …
Imaging of the β-cells of the islets of Langerhans
WJ Malaisse, K Maedler - Diabetes research and clinical practice, 2012 - Elsevier
The major aim of this paper is to review the present status of the techniques for the non-
invasive imaging and quantification of insulin-producing pancreatic islet β-cells. Emphasis is …
invasive imaging and quantification of insulin-producing pancreatic islet β-cells. Emphasis is …
Multivalent glibenclamide to generate islet specific imaging probes
A Babič, S Lamprianou, L Vinet, N Stransky-Heilkron… - Biomaterials, 2016 - Elsevier
The monitoring of diabetes mellitus, as it develops and becomes clinically evident, remains
a major challenge for diagnostic imaging in clinical practice. Here we present a novel …
a major challenge for diagnostic imaging in clinical practice. Here we present a novel …