DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Chemistries for DNA nanotechnology

M Madsen, KV Gothelf - Chemical reviews, 2019 - ACS Publications
The predictable nature of DNA interactions enables the programmable assembly of highly
advanced 2D and 3D DNA structures of nanoscale dimensions. The access to ever larger …

Tetrahedral DNA nanostructures for effective treatment of cancer: advances and prospects

J Yan, X Zhan, Z Zhang, K Chen, M Wang… - Journal of …, 2021 - Springer
Recently, DNA nanostructures with vast application potential in the field of biomedicine,
especially in drug delivery. Among these, tetrahedral DNA nanostructures (TDN) have …

[HTML][HTML] Advances in biological applications of self-assembled DNA tetrahedral nanostructures

S Li, T Tian, T Zhang, X Cai, Y Lin - Materials Today, 2019 - Elsevier
In recent years, there has been a rapid progress in the development of DNA nanomaterials
for biological applications. Owing to their unsurpassed editability, various DNA …

A camptothecin‐grafted DNA tetrahedron as a precise nanomedicine to inhibit tumor growth

J Zhang, Y Guo, F Ding, G Pan, X Zhu… - Angewandte …, 2019 - Wiley Online Library
Most chemotherapeutics are hydrophobic molecules and need to be converted into
hydrophilic form before administration. Based on the excellent hydrophilicity and …

Drug delivery by a self-assembled DNA tetrahedron for overcoming drug resistance in breast cancer cells

KR Kim, DR Kim, T Lee, JY Yhee, BS Kim… - Chemical …, 2013 - pubs.rsc.org
A DNA tetrahedron is employed for efficient delivery of doxorubicin into drug-resistant breast
cancer cells. The drug delivered with the DNA nanoconstruct is considerably cytotoxic …

Design and fine-tuning redox potentials of metalloproteins involved in electron transfer in bioenergetics

P Hosseinzadeh, Y Lu - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2016 - Elsevier
Redox potentials are a major contributor in controlling the electron transfer (ET) rates and
thus regulating the ET processes in the bioenergetics. To maximize the efficiency of the ET …

DNA as a powerful tool for morphology control, spatial positioning, and dynamic assembly of nanoparticles

LH Tan, H **ng, Y Lu - Accounts of chemical research, 2014 - ACS Publications
Conspectus Several properties of nanomaterials, such as morphologies (eg, shapes and
surface structures) and distance dependent properties (eg, plasmonic and quantum …

Superlarge, Rigidified DNA Tetrahedron with a Y-Shaped Backbone for Organizing Biomolecules Spatially and Maintaining Their Full Bioactivity

W Wang, W Wang, Y Chen, M Lin, YR Chen, R Zeng… - ACS …, 2024 - ACS Publications
A major impediment to the clinical translation of DNA tiling nanostructures is a technical
bottleneck for the programmable assembly of DNA architectures with well-defined local …

[HTML][HTML] DNA tetrahedral nanostructures for the biomedical application and spatial orientation of biomolecules

W Wang, M Lin, W Wang, Z Shen, ZS Wu - Bioactive Materials, 2024 - Elsevier
DNA not only plays a vital role in nature as fundamental hereditary material for storing
genetic material, but also serves as well-defined functional material, for example, building …