The endothelium, a cellular monolayer lining the blood vessel wall, plays a critical role in
maintaining multiorgan health and homeostasis. Endothelial functions in health include …

Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …

Atherosclerosis (AS) is the fundamental pathological state of many serious vascular
diseases, characterized by disorders of lipid metabolism. Ferroptosis is a type of regulated …

The concept of cell death has been expanded beyond apoptosis and necrosis to additional
forms, including necroptosis, pyroptosis, autophagy, and ferroptosis. These cell death …

Ischemic heart disease (IHD) is the leading cause of disability and mortality worldwide.
Reactive oxygen species (ROS) have been shown to play key roles in the progression of …

Atherosclerosis, a chronic multifactorial disease, is closely related to the development of
cardiovascular diseases and is one of the predominant causes of death worldwide. Normal …

Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …

Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …

Regenerative repair of the brain after traumatic brain injury (TBI) remains an extensive
clinical challenge, inspiring intensified interest in therapeutic approaches to explore superior …

Combining existing drug therapy is essential in develo** new therapeutic agents in
disease prevention and treatment. In preclinical investigations, combined effect of certain …