The Nuclear factor erythroid2-related factor2 (Nrf2), a master regulator of redox
homoeostasis, is a key transcription factor regulating a wide array of genes for antioxidant …

Living organisms come under attack from multiple environmental factors, which can lead to
the production of reactive oxygen species (ROS) and electrophiles. This results in oxidative …

Oxidative insult, inflammation, apoptosis and autophagy play a pivotal role in the etiology of
diabetic nephropathy, a global health concern. Ferulic acid, a phytochemical, is reported to …

Although profoundly studied, etiology of pancreatic cancer (PC) is still rather scarce. Some
of established risk factors of PC are connected to an increased cadmium (Cd) body burden …

Oxidative stress plays a crucial role in the progression of diabetic nephropathy in
hyperglycemic conditions. It has already been reported that mangiferin, a natural C-glucosyl …

Background Deregulation in prostaglandin (PG) biosynthesis, severe oxidative stress,
inflammation and apoptosis contribute to the pathogenesis of nonsteroidal anti-inflammatory …

Background: Cytochrome monooxygenases P450 enzymes (CYPs) are terminal oxidases,
belonging to the multi-gene family of heme-thiolate enzymes and located in multiple sites of …

Background Mangiferin is a polyphenolic xanthonoid with remarkable antioxidant activity.
Oxidative stress plays the key role in tert-butyl hydroperoxide (tBHP) induced renal cell …

Abstract Hexavalent chromium, Cr (VI), is an environmental toxicant and is associated with
hepatotoxicity. However, very little is known about the intracellular antioxidant defense …

Mangiferin (MAG), a natural xanthone mainly derived from mangoes, possesses great
antioxidative potentials. The present study has been carried out to investigate the hepato …