Virus-like particle vaccines: immunology and formulation for clinical translation

B Donaldson, Z Lateef, GF Walker… - Expert review of …, 2018 - Taylor & Francis
Introduction: Virus-like particle (VLP) vaccines face significant challenges in their translation
from laboratory models, to routine clinical administration. While some VLP vaccines thrive …

Comprehensive review on current interventions, diagnostics, and nanotechnology perspectives against SARS-CoV-2

DS Chauhan, R Prasad, R Srivastava… - Bioconjugate …, 2020 - ACS Publications
The coronavirus disease 2019 (COVID-19) has dramatically challenged the healthcare
system of almost all countries. The authorities are struggling to minimize the mortality along …

Nanotechnology‐facilitated vaccine development during the coronavirus disease 2019 (COVID‐19) pandemic

Z Wang, K Cui, U Costabel, X Zhang - Exploration, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) continually poses a significant threat to the
human race, and prophylactic vaccination is the most potent approach to end this pandemic …

Lipid peroxidation causes endosomal antigen release for cross-presentation

I Dingjan, DRJ Verboogen, LM Paardekooper… - Scientific reports, 2016 - nature.com
Dendritic cells (DCs) present foreign antigen in major histocompatibility complex (MHC)
class I molecules to cytotoxic T cells in a process called cross-presentation. An important …

Advancements in protein nanoparticle vaccine platforms to combat infectious disease

N Butkovich, E Li, A Ramirez… - Wiley …, 2021 - Wiley Online Library
Infectious diseases are a major threat to global human health, yet prophylactic treatment
options can be limited, as safe and efficacious vaccines exist only for a fraction of all …

Targeting the MHC Class II antigen presentation pathway in cancer immunotherapy

J Thibodeau, MC Bourgeois-Daigneault… - …, 2012 - Taylor & Francis
The success of immunotherapy relies on the participation of all arms of the immune system
and the role of CD4+ T lymphocytes in preventing tumor growth is now well established …

Potentiating cancer immunotherapy using papaya mosaic virus-derived nanoparticles

MÈ Lebel, K Chartrand, E Tarrab, P Savard… - Nano …, 2016 - ACS Publications
The recent development of novel immunotherapies is revolutionizing cancer treatment.
These include, for example, immune checkpoint blockade, immunomodulation, or …

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform

J Denis, E Acosta-Ramirez, Y Zhao, ME Hamelin… - Vaccine, 2008 - Elsevier
With the emergence of highly virulent influenza viruses and the consequent risk of
pandemics, new approaches to designing universal influenza vaccines are urgently needed …

Combating human viral diseases: will plant-based vaccines be the answer?

S Venkataraman, K Hefferon, A Makhzoum… - Vaccines, 2021 - mdpi.com
Molecular pharming or the technology of application of plants and plant cell culture to
manufacture high-value recombinant proteins has progressed a long way over the last three …

Plant virus nanoparticles: Novel and robust nanocarriers for drug delivery and imaging

E Alemzadeh, A Dehshahri, K Izadpanah… - Colloids and Surfaces B …, 2018 - Elsevier
Nanoparticles have been gained much attention for biomedical applications. A promising
type of nanocarriers is viral nanoparticles (VNPs) which are natural bio-nanomaterials …