Xpert MTB/RIF and Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance in adults

JS Zifodya, I Schiller, N Dendukuri… - Cochrane Database …, 2019 - cochranelibrary.com
Background Xpert MTB/RIF (Xpert MTB/RIF) and Xpert MTB/RIF Ultra (Xpert Ultra), the
newest version, are the only World Health Organization (WHO)‐recommended rapid tests …

Xpert® MTB/RIF assay for pulmonary tuberculosis and rifampicin resistance in adults

KR Steingart, H Sohn, I Schiller… - Cochrane database …, 2013 - cochranelibrary.com
Background Accurate and rapid detection of tuberculosis (TB) and drug resistance are
critical for improving patient care and decreasing the spread of TB. Xpert® MTB/RIF assay …

The South African tuberculosis care cascade: estimated losses and methodological challenges

P Naidoo, G Theron, MX Rangaka… - The Journal of …, 2017 - academic.oup.com
Background While tuberculosis incidence and mortality are declining in South Africa,
meeting the goals of the End TB Strategy requires an invigorated programmatic response …

Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis

AK Detjen, AR DiNardo, J Leyden… - The lancet respiratory …, 2015 - thelancet.com
Background Microbiological confirmation of childhood tuberculosis is rare because of the
difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to …

Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled …

G Theron, L Zijenah, D Chanda, P Clowes, A Rachow… - The Lancet, 2014 - thelancet.com
Summary Background The Xpert MTB/RIF test for tuberculosis is being rolled out in many
countries, but evidence is lacking regarding its implementation outside laboratories, ability to …

Xpert Ultra versus Xpert MTB/RIF for pulmonary tuberculosis and rifampicin resistance in adults with presumptive pulmonary tuberculosis

JS Zifodya, JS Kreniske, I Schiller… - Cochrane Database …, 2021 - cochranelibrary.com
Background Xpert MTB/RIF and Xpert MTB/RIF Ultra (Xpert Ultra) are World Health
Organization (WHO)‐recommended rapid tests that simultaneously detect tuberculosis and …

[HTML][HTML] Point of care diagnostics for tuberculosis

AL García-Basteiro, A DiNardo, B Saavedra, DR Silva… - Pulmonology, 2018 - Elsevier
The goals of the End TB strategy, which aims to achieve a 90% reduction in tuberculosis
(TB) incidence and a 95% reduction in TB mortality by 2035, will not be achieved without …

Impact of replacing smear microscopy with Xpert MTB/RIF for diagnosing tuberculosis in Brazil: a stepped-wedge cluster-randomized trial

B Durovni, V Saraceni, S van den Hof, A Trajman… - PLoS …, 2014 - journals.plos.org
Background Abundant evidence on Xpert MTB/RIF accuracy for diagnosing tuberculosis
(TB) and rifampicin resistance has been produced, yet there are few data on the population …

Do high rates of empirical treatment undermine the potential effect of new diagnostic tests for tuberculosis in high-burden settings?

G Theron, J Peter, D Dowdy, I Langley… - The Lancet infectious …, 2014 - thelancet.com
In tuberculosis-endemic settings, patients are often treated empirically, meaning that they
are placed on treatment based on clinical symptoms or tests that do not provide a …

Rapid, point-of-care diagnosis of tuberculosis with novel Truenat assay: cost-effectiveness analysis for India's public sector

DJ Lee, N Kumarasamy, SC Resch… - PLoS …, 2019 - journals.plos.org
Background Truenat is a novel molecular assay that rapidly detects tuberculosis (TB) and
rifampicin-resistance. Due to the portability of its battery-powered testing platform, it may be …