Massively parallel sample preparation for multiplexed single-cell proteomics using nPOP

A Leduc, L Khoury, J Cantlon, S Khan, N Slavov - Nature protocols, 2024 - nature.com
Single-cell proteomics by mass spectrometry (MS) allows the quantification of proteins with
high specificity and sensitivity. To increase its throughput, we developed nano-proteomic …

Formaldehyde Fixation Helps Preserve the Proteome State during Single-Cell Proteomics Sample Processing and Analysis

I Piga, C Koenig, M Lechner, P Sabatier… - Journal of Proteome …, 2025 - ACS Publications
Mass spectrometry-based single-cell proteomics (SCP) is gaining momentum but remains
limited to a few laboratories due to the high costs and specialized expertise required. The …