Extracellular vesicles (EVs) have emerged as a novel cell‐free strategy for the treatment of
many diseases including cancer. As a result of their natural properties to mediate cell‐to‐cell …

As a natural polysaccharide, dextran and its derivatives have gained great attention in the
development of delivery systems for pharmaceutical and medical applications. In recent …

Chemoresistance and metastasis are the major challenges for the current ovarian cancer
treatment. Understanding the mechanisms of ovarian cancer progression and metastasis is …

Multidrug resistance (MDR) seriously limits the clinical application of chemotherapy. A
mechanism underlying MDR is the overexpression of efflux transporters associated with …

Single-cell diagnosis of cancer drug resistance is highly relevant for cancer treatment, as it
can be used to identify the subpopulations of drug-resistant cancer cells, reveal the …

Background Spinal cord injury (SCI) is an inflammatory condition, and excessive adenosine
triphosphate (ATP) is released into the extracellular space, which can be catabolized into …

Exosomes are a category of extracellular vesicles with a size ranging from 40 to 160 nm,
which can be secreted by multiple cells in the tumor microenvironment. Exosomes serve as …

Cancer, caused by uncontrolled proliferation of abnormal cells, has long been a global
public health issue. For decades, natural products have been proven to be an essential …

Epithelial ovarian cancer (EOC) is one of the deadliest gynaecological malignancies. The
late diagnosis is frequent due to the absence of specific symptomatology and the molecular …

Clinically, the primary cause of chemotherapy failure belongs to the occurrence of cancer
multidrug resistance (MDR), which directly leads to the recurrence and metastasis of cancer …