Focuses on tissue engineering as paradigm for periodontal regeneration based on
molecular and cell biology. Reestablishment of soft tissue attachment on root surface; …

Abstract The Cbfa1/Runx2 is an important transcription factor necessary for osteoblast
differentiation and bone formation. However, the signaling pathways regulating Runx2 …

Integrin-mediated cell adhesion is central to cell survival, differentiation and motility. Many
cell responses induced by integrins require both receptor occupancy and receptor …

Extracellular signal-regulated kinases (Erks), members of the mitogen-activated protein
kinase superfamily, play an important role in cell proliferation and differentiation. In this study …

Background There is little information on specific interactions between dermal fibroblasts
and epidermal keratinocytes. The use of engineered skin equivalents consisting of …

The Cbfa1/Runx2 transcription factor is essential for osteoblast differentiation. However,
levels of Runx2 are often not well correlated with its transcriptional activity suggesting that …

Transforming growth factor-β (TGF-β) is an intriguing cytokine exhibiting dual activities in
malignant disease. It is an important mediator of cancer invasion, metastasis and …

The nature of the extracellular matrix (ECM) is crucial in regulating cell functions via cell–
matrix interactions, cytoskeletal organization, and integrin-mediated signaling. In bone, the …

Integrin-mediated adhesion of epithelial cells to extracellular matrix (ECM) proteins induces
prolonged tyrosine phosphorylation and partial activation of epidermal growth factor …

Cross-talk between the major angiogenic growth factor, VEGF, and integrin cell adhesion
receptors has emerged recently as a critical factor in the regulation of angiogenesis and …