Origins and immunopathogenesis of autoimmune central nervous system disorders

S Ramanathan, F Brilot, SR Irani, RC Dale - Nature Reviews Neurology, 2023 - nature.com
The field of autoimmune neurology is rapidly evolving, and recent discoveries have
advanced our understanding of disease aetiologies. In this article, we review the key …

Neurological adverse events of immune checkpoint inhibitors and the development of paraneoplastic neurological syndromes

A Farina, M Villagrán-García, A Vogrig… - The Lancet …, 2024 - thelancet.com
Immune checkpoint inhibitors, a class of oncological treatments that enhance antitumour
immunity, can trigger neurological adverse events closely resembling paraneoplastic …

Updated diagnostic criteria for paraneoplastic neurologic syndromes

F Graus, A Vogrig, S Muñiz-Castrillo… - Neurology …, 2021 - neurology.org
Objective The contemporary diagnosis of paraneoplastic neurologic syndromes (PNSs)
requires an increasing understanding of their clinical, immunologic, and oncologic …

Molecular mimicry in multisystem inflammatory syndrome in children

A Bodansky, RC Mettelman, JJ Sabatino Jr… - Nature, 2024 - nature.com
Multisystem inflammatory syndrome in children (MIS-C) is a severe, post-infectious sequela
of SARS-CoV-2 infection,, yet the pathophysiological mechanism connecting the infection to …

Paraneoplastic neurological syndromes: a practical approach to diagnosis and management

S Binks, C Uy, J Honnorat, SR Irani - Practical Neurology, 2022 - pn.bmj.com
Paraneoplastic neurological syndromes (PNS) are the immune-mediated effects of a remote
cancer and are characterised by an autoantibody response against antigens expressed by …

Autoimmune disorders of the nervous system: pathophysiology, clinical features, and therapy

S Bhagavati - Frontiers in neurology, 2021 - frontiersin.org
Remarkable discoveries over the last two decades have elucidated the autoimmune basis of
several, previously poorly understood, neurological disorders. Autoimmune disorders of the …

Paraneoplastic neurologic disorders

M Gilligan, C McGuigan, A McKeon - Current neurology and neuroscience …, 2023 - Springer
Abstract Purpose of Review To provide an overview and highlight recent updates in the field
of paraneoplastic neurologic disorders. Recent Findings The prevalence of paraneoplastic …

Antibody-mediated autoimmune diseases of the CNS: challenges and approaches to diagnosis and management

E Sechi, EP Flanagan - Frontiers in neurology, 2021 - frontiersin.org
Antibody-mediated disorders of the central nervous system (CNS) are increasingly
recognized as neurologic disorders that can be severe and even life-threatening but with the …

Autoimmune encephalitis criteria in clinical practice

E Orozco, C Valencia-Sanchez, J Britton… - Neurology: Clinical …, 2023 - neurology.org
Background and Objectives To assess the clinical practice applicability of autoimmune
encephalitis (AE) criteria (2016). Methods Medical records of 538 adults diagnosed with AE …

Paraneoplastic neurological syndromes: clinical presentations and management

MF Devine, N Kothapalli, M Elkhooly… - Therapeutic …, 2021 - journals.sagepub.com
We provide an overview of the varied presentations of paraneoplastic neurological
syndromes. We also review the onconeural antibodies and their particular oncological and …