Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training

B Egan, AP Sharples - Physiological Reviews, 2023 - journals.physiology.org
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions

MD Roberts, JJ McCarthy… - Physiological …, 2023 - journals.physiology.org
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Molecular mechanisms of exercise contributing to tissue regeneration

J Chen, R Zhou, Y Feng, L Cheng - Signal Transduction and Targeted …, 2022 - nature.com
Physical activity has been known as an essential element to promote human health for
centuries. Thus, exercise intervention is encouraged to battle against sedentary lifestyle …

Hamstring Strain Injury in Athletes: Clinical Practice Guidelines Linked to the International Classification of Functioning, Disability and Health From the Academy of …

RL Martin, MT Cibulka, LA Bolgla, TA Koc Jr… - Journal of Orthopaedic & …, 2022 - jospt.org
Hamstring strain injury (HSI) may result in considerable impairment, activity limitation, and
participation restriction, including time lost from competitive sports. This CPG includes sports …

[HTML][HTML] Molecular aspects of the exercise response and training adaptation in skeletal muscle

R Furrer, C Handschin - Free Radical Biology and Medicine, 2024 - Elsevier
Skeletal muscle plasticity enables an enormous potential to adapt to various internal and
external stimuli and perturbations. Most notably, changes in contractile activity evoke a …

Muscle-specific cellular and molecular adaptations to late-life voluntary concurrent exercise

CM Dungan, CR Brightwell, Y Wen, CJ Zdunek… - Function, 2022 - academic.oup.com
Murine exercise models can provide information on factors that influence muscle
adaptability with aging, but few translatable solutions exist. Progressive weighted wheel …

The myonuclear domain in adult skeletal muscle fibres: past, present and future

JR Bagley, LT Denes, JJ McCarthy… - The Journal of …, 2023 - Wiley Online Library
Most cells in the body are mononuclear whereas skeletal muscle fibres are uniquely
multinuclear. The nuclei of muscle fibres (myonuclei) are usually situated peripherally which …

The mini-IDLE 3D biomimetic culture assay enables interrogation of mechanisms governing muscle stem cell quiescence and niche repopulation

E Jacques, Y Kuang, AP Kann, F Le Grand, RS Krauss… - Elife, 2022 - elifesciences.org
Adult skeletal muscle harbours a population of muscle stem cells (MuSCs) that are required
for repair after tissue injury. In youth, MuSCs return to a reversible state of cell-cycle arrest …

TAZ stimulates exercise‐induced muscle satellite cell activation via Pard3–p38 MAPK–TAZ signalling axis

KM Kim, GD Yoo, W Heo, HT Oh, J Park… - Journal of cachexia …, 2023 - Wiley Online Library
Background Exercise stimulates the activation of muscle satellite cells, which facilitate the
maintenance of stem cells and their myogenic conversion during muscle regeneration …

Epigenetic evidence for distinct contributions of resident and acquired myonuclei during long-term exercise adaptation using timed in vivo myonuclear labeling

KA Murach, CM Dungan… - American Journal of …, 2022 - journals.physiology.org
Muscle fibers are syncytial postmitotic cells that can acquire exogenous nuclei from resident
muscle stem cells, called satellite cells. Myonuclei are added to muscle fibers by satellite …