Background: Intra-articular injection of adipose-derived stem cells, which are divided into
adipose-derived mesenchymal stem cells (ASCs) and adipose-derived stromal vascular …

Background: Focal cartilage lesions represent a common source of knee pain and disability,
with the potential for the development and progression of osteoarthritis. Currently …

Background: Lesions of the articular cartilage, with or without involvement of the
subchondral bone, are a common cause of pain and dysfunction in the knee. Although …

Background: There are limited randomized controlled trials with long-term outcomes
comparing autologous chondrocyte implantation (ACI) versus alternative forms of surgical …

The Working Group of the German Orthopedic and Trauma Society (DGOU) on Tissue
Regeneration has published recommendations on the indication of different surgical …

Functional cartilage regeneration remains difficult to achieve despite decades of research.
Dozens of commercial products have been proposed, with each targeting different facets of …

Focal chondral defects of the knee are common and their management is challenging. This
study investigated the efficacy and safety of Autologous Matrix-Induced Chondrogenesis …

Background Chondral defects of the knee can be identified in up to 60% of patients
undergoing knee arthroscopy. The use of Autologous Matrix Induced Chondrogenesis …

Objective Despite an increased interest in treatment options for cartilage lesions of the knee,
the relationship between lesion characteristics and the symptoms they elicit is not well …

Purpose Patellar cartilage lesions are a frequent and challenging finding in orthopaedic
clinical practice. This study aimed to evaluate a chitosan‐based scaffold's mid‐term clinical …