Abstract Barrigenol-like triterpenoids (BATs), which contain an unusual oleanane substituted
by many hydroxyl groups as the skeleton, are subdivided into five subtypes: barrigenol A 1 …

Saponins are a group of compounds used in clinical practice in the management of several
diseases. Escin is a natural mixture of triterpene saponins which mainly consist of several …

Background: Benign prostatic hyperplasia (BPH) is the most common urogenital condition in
aging males, while inflammation and tissue proliferation constitute the main …

Tribulus terrestris L. is well distributed in Asia and applied to treat inflammation,
cardiovascular and cerebrovascular illness, cancer, oxidative stress, hormone imbalance …

Hyperactivity of HPA axis results in intestinal dysfunction, which may play a role in brain
injury caused by ischemic stroke (IS). Escin shows a neuroprotective effect but it may not …

Escin, as an internally applied anti-inflammatory agent, has been widely used in the
treatment of inflammation and edema resulting from trauma or operation in the clinic …

Glucocorticoids are drugs that are widely used to suppress inflammation and the activation
of the immune system. However, the prolonged use or at high doses of glucocorticoid can …

In China, escin has been widely used in the clinic as a potent anti‑inflammatory drug.
Previous studies have indicated that escin exerts its anti-inflammatory effect by enhancing …

Ethnopharmacological relevance Tribulus terrestris L., as an annual herb plant from
Zygophyllaceae, exhibits many biological activities, and its main chemical constituents are …

Escin is a triterpenoid saponin extracted from the fruit of Aesculus wilsonii Rehd. and
Aesculus hippocastanum (Hippocastanaceae). Clinically, it is widely used in the treatment of …