Insecticidal proteins from the bacterium Bacillus thuringiensis (Bt) are used in sprayable
formulations or produced in transgenic crops as the most successful alternatives to synthetic …

Arthropods have well adapted to the vast array of chemicals they encounter in their
environment. Whether these xenobiotics are plant allelochemicals or anthropogenic …

Highlights•ABCC2-and ABCC3-based Cry1 resistance was extended to several Lepidoptera
species.•ABCG modulates cuticle thickness in Culex pipiens and contributes to deltamethrin …

Ongoing host–pathogen interactions can trigger a coevolutionary arms race, while genetic
diversity within the host can facilitate its adaptation to pathogens. Here, we used the …

The evolution of insect resistance to pesticides poses a continuing threat to agriculture and
human health. While much is known about the proximate molecular and biochemical …

ATP-binding cassette (ABC) transporters, a large class of transmembrane proteins, are
widely found in organisms and play an important role in the transport of xenobiotics. Insect …

The arms race between entomopathogenic bacteria and their insect hosts is an excellent
model for decoding the intricate coevolutionary processes of host-pathogen interaction …

Clustered regularly interspaced short palindromic repeats (CRISPR) and the CRISPR-
associated gene Cas9 represent an invaluable system for the precise editing of genes in …

Extensive use of chemical pesticides poses a great threat to the environment and food
safety. The discovery of Bacillus thuringiensis (Bt) toxins with effective insecticidal activity …

Maintaining fitness during pathogen infection is vital for host survival as an excessive
response can be as detrimental as the infection itself. Fitness costs are frequently associated …