Adropin's role in energy homeostasis and metabolic disorders
Adropin is a novel 76-amino acid-peptide that is expressed in different tissues and cells
including the liver, pancreas, heart and vascular tissues, kidney, milk, serum, plasma and …
including the liver, pancreas, heart and vascular tissues, kidney, milk, serum, plasma and …
Adipose tissue secretion pattern influences β-cell wellness in the transition from obesity to type 2 diabetes
The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …
Irisin alleviates FFA induced β-cell insulin resistance and inflammatory response through activating PI3K/AKT/FOXO1 signaling pathway
S Zheng, N Chen, X Kang, Y Hu, S Shi - Endocrine, 2022 - Springer
Purpose Type 2 diabetes mellitus is characterized by insulin resistance and β-cell
dysfunction. Elevated free fatty acids-induced lipotoxicity may play a vital role in the …
dysfunction. Elevated free fatty acids-induced lipotoxicity may play a vital role in the …
Type 2 diabetes and Alzheimer's disease: the emerging role of cellular lipotoxicity
Type 2 diabetes (T2D) and Alzheimer's diseases (AD) represent major health issues that
have reached alarming levels in the last decades. Although growing evidence demonstrates …
have reached alarming levels in the last decades. Although growing evidence demonstrates …
Irisin/PGC-1α/FNDC5 pathway in Parkinson's disease: truth under the throes
Parkinson's disease (PD) is considered one of the most common neurodegenerative brain
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …
diseases which involves the deposition of α-synuclein. Irisin hormone, a newly discovered …
Irisin: an anti-inflammatory exerkine in aging and redox-mediated comorbidities
Human beings lead largely sedentary lives. From an evolutionary perspective, such lifestyle
is not beneficial to health. Exercise can promote many enabling pathways, particularly …
is not beneficial to health. Exercise can promote many enabling pathways, particularly …
Role of Irisin in Endocrine and Metabolic Disorders—Possible New Therapeutic Agent?
Irisin is a novel hormone that provides a possible solution for the treatment of metabolic
disorders. Discovered in 2012 by Boström et al., irisin very quickly became an interesting …
disorders. Discovered in 2012 by Boström et al., irisin very quickly became an interesting …
[HTML][HTML] Prevention of Alzheimer's disease through diet: an exploratory review
NZ Bhuiyan, MK Hasan, Z Mahmud, MS Hossain… - Metabolism Open, 2023 - Elsevier
Introduction This exploratory review article describes about the genetic factors behind
Alzheimer's disease (AD), their association with foods, and their relationships with cognitive …
Alzheimer's disease (AD), their association with foods, and their relationships with cognitive …
Development, regeneration, and physiological expansion of functional β-cells: Cellular sources and regulators
МB Chernysheva, ЕS Ruchko, МV Karimova… - Frontiers in Cell and …, 2024 - frontiersin.org
Pancreatic regeneration is a complex process observed in both normal and pathological
conditions. The aim of this review is to provide a comprehensive understanding of the …
conditions. The aim of this review is to provide a comprehensive understanding of the …
Exploring the potential roles of apelin, visfatin, and irisin in energy regulation in farm animals: an overview
B Shokrollahi, SS Jang, HJ Lee, HI Ahmad… - Frontiers in Veterinary …, 2024 - frontiersin.org
Adipose tissue, both intricate and fundamental to physiological functions, comprises cell
types, including adipocytes, pivotal in secreting bioactive peptides known as …
types, including adipocytes, pivotal in secreting bioactive peptides known as …