Heterocyclic scaffolds: centrality in anticancer drug development

I Ali, M Nadeem Lone, Z A. Al-Othman… - Current drug …, 2015 - benthamdirect.com
Cancer has been cursed for human beings for long time. Millions people lost their lives due
to cancer. Despite of the several anticancer drugs available, cancer cannot be cured; …

Application of Palladium Based Precatalytic Systems in the Suzuki‐Miyaura Cross‐Coupling Reactions of Chloro‐Heterocycles

S Bhaskaran, MSA Padusha, AM Sajith - ChemistrySelect, 2020 - Wiley Online Library
Carbon‐Carbon bond forming reactions using Suzuki‐Miyaura cross‐coupling (SMC)
technology to construct aryl‐aryl, aryl‐heteroaryl or heteroaryl‐heteroaryl linkages continues …

Visible-light-induced, metal-free carbene insertion into B–H bonds between acylsilanes and pinacolborane

JH Ye, L Quach, T Paulisch… - Journal of the American …, 2019 - ACS Publications
Carbene insertion reactions with B–H bonds are a challenging but promising method for the
synthesis of organoboranes. Herein, we report visible-light-induced B–H insertions of HBpin …

Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles: Substrate scope and mechanistic investigation

MA Düfert, KL Billingsley… - Journal of the American …, 2013 - ACS Publications
The Suzuki-Miyaura cross-coupling of unprotected, nitrogen-rich heterocycles using
precatalysts P1 or P2 is reported. The procedure allows for the reaction of variously …

Nickel-catalyzed Suzuki–Miyaura coupling of aliphatic amides

TB Boit, NA Weires, J Kim, NK Garg - ACS catalysis, 2018 - ACS Publications
We report the Ni-catalyzed Suzuki–Miyaura coupling of aliphatic amide derivatives. Prior
studies have shown that aliphatic amide derivatives can undergo Ni-catalyzed carbon …

Biosynthesis, characterization and catalytic activity of an Ag/zeolite nanocomposite for base-and ligand-free oxidative hydroxylation of phenylboronic acid and …

A Hatamifard, M Nasrollahzadeh… - New Journal of Chemistry, 2016 - pubs.rsc.org
This paper reports on the synthesis and use of an Ag/zeolite nanocomposite as a separable
catalyst for the ligand-free hydroxylation of phenylboronic acid to phenol and the reduction …

Micellar system in copper-catalysed hydroxylation of arylboronic acids: facile access to phenols

K Inamoto, K Nozawa, M Yonemoto… - Chemical …, 2011 - pubs.rsc.org
Micellar system in copper-catalysed hydroxylation of arylboronic acids: facile access to phenols -
Chemical Communications (RSC Publishing) DOI:10.1039/C1CC14974A Royal Society of …

Palladium-catalyzed C–O bond formation: direct synthesis of phenols and aryl/alkyl ethers from activated aryl halides

G Chen, ASC Chan, FY Kwong - Tetrahedron Letters, 2007 - Elsevier
A simple and efficient palladium-catalyzed carbon–oxygen bond formation is reported. The
palladium-tri-tert-butylphosphine complex was found to be effective in converting …

Nitrogen-carbon bond formation from N2 and CO2 promoted by a hafnocene dinitrogen complex yields a substituted hydrazine

WH Bernskoetter, E Lobkovsky… - Angewandte Chemie …, 2007 - collaborate.princeton.edu
Abstract (Chemical Equation Presented) Hafnocene and hydrazine: The addition of two
equivalents of carbon dioxide to the hafnocene dinitrogen complex 1 proved effective for the …

Mechanistic Studies and Data Science-Guided Exploration of Bromotetrazine Cross-Coupling

LV Hoff, GA Chesnokov, A Linden, K Gademann - ACS Catalysis, 2022 - ACS Publications
A thorough mechanistic investigation of the Pd-catalyzed and Ag-mediated cross-coupling of
the monosubstituted tetrazine 3-bromo-1, 2, 4, 5-tetrazine with boronic acids is reported. The …