[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …
Overcoming the blood–brain barrier for the therapy of malignant brain tumor: current status and prospects of drug delivery approaches
Besides the broad development of nanotechnological approaches for cancer diagnosis and
therapy, currently, there is no significant progress in the treatment of different types of brain …
therapy, currently, there is no significant progress in the treatment of different types of brain …
Nanomaterial based drug delivery systems for the treatment of neurodegenerative diseases
With an aging population that has been increasing in recent years, the need for the
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …
development of therapeutic approaches for treatment of neurodegenerative disorders (ND) …
Antioxidants and nanotechnology: promises and limits of potentially disruptive approaches in the treatment of central nervous system diseases
Many central nervous system (CNS) diseases are still incurable and only symptomatic
treatments are available. Oxidative stress is suggested to be a common hallmark, being able …
treatments are available. Oxidative stress is suggested to be a common hallmark, being able …
Brain injury-induced dysfunction of the blood brain barrier as a risk for dementia
EE Abrahamson, MD Ikonomovic - Experimental neurology, 2020 - Elsevier
The blood-brain barrier (BBB) is a complex and dynamic physiological interface between
brain parenchyma and cerebral vasculature. It is composed of closely interacting cells and …
brain parenchyma and cerebral vasculature. It is composed of closely interacting cells and …
Astrocyte-targeted siRNA delivery by adenosine-functionalized LNP in mouse TBI model
H **ao, O Amarsaikhan, Y Zhao, X Yu, X Hu… - … Therapy Nucleic Acids, 2023 - cell.com
Traumatic brain injury (TBI) induces pro-inflammatory polarization of astrocytes and causes
secondary disruption of the blood-brain barrier (BBB) and brain damage. Herein, we report a …
secondary disruption of the blood-brain barrier (BBB) and brain damage. Herein, we report a …
Exploring the potential of nanotechnology in pediatric healthcare: advances, challenges, and future directions
The utilization of nanotechnology has brought about notable advancements in the field of
pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and …
pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and …
[HTML][HTML] Nanoparticle-based technology approaches to the management of neurological disorders
Neurological disorders are the most devastating and challenging diseases associated with
the central nervous system (CNS). The blood-brain barrier (BBB) maintains homeostasis of …
the central nervous system (CNS). The blood-brain barrier (BBB) maintains homeostasis of …
[HTML][HTML] Microfluidic development of brain-derived neurotrophic factor loaded solid lipid nanoparticles: an in vitro evaluation in the post-traumatic brain injury …
F Sommonte, I Arduino, RM Iacobazzi, L Laera… - Journal of Drug Delivery …, 2024 - Elsevier
Microfluidic-based nanoscale drug delivery systems have risen to prominence in the field of
precision nanomedicine in recent years. This intriguing innovation could provide unique …
precision nanomedicine in recent years. This intriguing innovation could provide unique …
Tailored reconstituted lipoprotein for site-specific and mitochondria-targeted cyclosporine a delivery to treat traumatic brain injury
The secondary damage in traumatic brain injury (TBI) can lead to lifelong disabilities,
bringing enormous economic and psychological burden to patients and their families …
bringing enormous economic and psychological burden to patients and their families …