Overview and considerations in bottom-up proteomics
RM Miller, LM Smith - Analyst, 2023 - pubs.rsc.org
Proteins are the key biological actors within cells, driving many biological processes integral
to both healthy and diseased states. Understanding the depth of complexity represented …
to both healthy and diseased states. Understanding the depth of complexity represented …
Computational methods for understanding mass spectrometry–based shotgun proteomics data
Computational proteomics is the data science concerned with the identification and
quantification of proteins from high-throughput data and the biological interpretation of their …
quantification of proteins from high-throughput data and the biological interpretation of their …
Enhanced protein isoform characterization through long-read proteogenomics
Background The detection of physiologically relevant protein isoforms encoded by the
human genome is critical to biomedicine. Mass spectrometry (MS)-based proteomics is the …
human genome is critical to biomedicine. Mass spectrometry (MS)-based proteomics is the …
X! TandemPipeline: a tool to manage sequence redundancy for protein inference and phosphosite identification
O Langella, B Valot, T Balliau… - Journal of proteome …, 2017 - ACS Publications
X! TandemPipeline is a software designed to perform protein inference and to manage
redundancy in the results of phosphosite identification by database search. It provides the …
redundancy in the results of phosphosite identification by database search. It provides the …
Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows
Metaproteomics has matured into a powerful tool to assess functional interactions in
microbial communities. While many metaproteomic workflows are available, the impact of …
microbial communities. While many metaproteomic workflows are available, the impact of …
Mass spectrometry–based protein identification in proteomics—a review
Statistically, accurate protein identification is a fundamental cornerstone of proteomics and
underpins the understanding and application of this technology across all elements of …
underpins the understanding and application of this technology across all elements of …
A critical analysis of research methods and experimental models to study the root canal microbiome
Endodontic microbiology deals with the study of the microbial aetiology and pathogenesis of
pulpal and periradicular inflammatory diseases. Research in endodontic microbiology …
pulpal and periradicular inflammatory diseases. Research in endodontic microbiology …
Challenges and promise at the interface of metaproteomics and genomics: an overview of recent progress in metaproteogenomic data analysis
H Schiebenhoefer, T Van Den Bossche… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The study of microbial communities based on the combined analysis of
genomic and proteomic data–called metaproteogenomics–has gained increased research …
genomic and proteomic data–called metaproteogenomics–has gained increased research …
Quantification of snake venom proteomes by mass spectrometry‐considerations and perspectives
The advent of soft ionization mass spectrometry‐based proteomics in the 1990s led to the
development of a new dimension in biology that conceptually allows for the integral analysis …
development of a new dimension in biology that conceptually allows for the integral analysis …
gpGrouper: a peptide grou** algorithm for gene-centric inference and quantitation of bottom-up proteomics data
In quantitative mass spectrometry, the method by which peptides are grouped into proteins
can have dramatic effects on downstream analyses. Here we describe gpGrouper, an …
can have dramatic effects on downstream analyses. Here we describe gpGrouper, an …