Pharmacology and toxicology are part of a much broader effort to understand the
relationship between chemistry and biology. While biomedicine has necessarily focused on …

Network science provides a set of tools for the characterization of the structure and
functional behavior of complex systems. Yet a major problem is to quantify how the structural …

Background Loss or disrupted expression of the FMR1 gene causes fragile X syndrome
(FXS), the most common monogenetic form of autism in humans. Although disruptions in …

Cognitive decline is commonly seen both in normal aging and in neurodegenerative and
neuropsychiatric diseases. Various experimental animal models represent a valuable tool to …

The imaging of neuronal activity using calcium indicators has become a staple of modern
neuroscience. However, without ground truths, there is a real risk of missing a significant …

Larval zebrafish that are exposed repeatedly to dark looming stimuli will quickly habituate to
these aversive signals and cease to respond with their stereotypical escape swims. A dark …

Background Autism spectrum disorder (ASD), like many neurodevelopmental disorders, has
complex and varied etiologies. Advances in genome sequencing have identified multiple …

Response variability is an essential and universal feature of sensory processing and
behavior. It arises from fluctuations in the internal state of the brain, which modulate how …

Visual systems have evolved to discriminate between different wavelengths of light. The
ability to perceive color, or specific light wavelengths, is important as color conveys crucial …

The zebrafish visual system has become a paradigmatic preparation for behavioral and
systems neuroscience. Around 40 types of retinal ganglion cells (RGCs) serve as matched …