RNA molecules can fold into intricate shapes that can provide an additional layer of control
of gene expression beyond that of their sequence. In this Review, we discuss the current …

RNAs fold into 3D structures that range from simple helical elements to complex tertiary
structures and quaternary ribonucleoprotein assemblies. The functions of many regulatory …

3′-untranslated regions (3′-UTRs) are the noncoding parts of mRNAs. Compared to
yeast, in humans, median 3′-UTR length has expanded approximately tenfold alongside …

RNA binding proteins (RBPs) orchestrate the production, processing, and function of
mRNAs. Here, we present the affinity landscapes of 78 human RBPs using an unbiased …

RNA-binding proteins (RBPs) play key roles in post-transcriptional regulation. Accurate
identification of RBP binding sites in multiple cell lines and tissue types from diverse species …

An emerging body of evidence indicates that post-transcriptional gene regulation relies not
only on the sequence of mRNAs but also on their folding into intricate secondary structures …

Cellular processes are the product of interactions between biomolecules, which associate to
form biologically active complexes. These interactions are mediated by intermolecular …

Most RNA processing occurs co-transcriptionally. We interrogated nascent pol II transcripts
by chemical and enzymatic probing and determined how the" nascent RNA structureome" …

The sorting of RNA molecules to subcellular locations facilitates the activity of spatially
restricted processes. We have analyzed subcellular transcriptomes of FMRP-null mouse …

RNA localization mechanisms have been intensively studied and include localized
protection of mRNA from degradation, diffusion-coupled local entrapment of mRNA, and …