Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Structure–reactivity–property relationships in covalent adaptable networks

V Zhang, B Kang, JV Accardo… - Journal of the American …, 2022 - ACS Publications
Polymer networks built out of dynamic covalent bonds offer the potential to translate the
control and tunability of chemical reactions to macroscopic physical properties. Under …

[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration

W Kim, Y Gwon, S Park, H Kim, J Kim - Bioactive Materials, 2023 - Elsevier
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Tailoring the Swelling‐Shrinkable Behavior of Hydrogels for Biomedical Applications

W Feng, Z Wang - Advanced Science, 2023 - Wiley Online Library
Hydrogels with tailor‐made swelling‐shrinkable properties have aroused considerable
interest in numerous biomedical domains. For example, as swelling is a key issue for blood …

Dynamic covalent hydrogels as biomaterials to mimic the viscoelasticity of soft tissues

S Tang, BM Richardson, KS Anseth - Progress in Materials Science, 2021 - Elsevier
The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …

Mechanics of 3D cell–hydrogel interactions: experiments, models, and mechanisms

FJ Vernerey, S Lalitha Sridhar, A Muralidharan… - Chemical …, 2021 - ACS Publications
Hydrogels are highly water-swollen molecular networks that are ideal platforms to create
tissue mimetics owing to their vast and tunable properties. As such, hydrogels are promising …

[HTML][HTML] In-plane implanting carbon rings into carbon nitride to intrigue nonradical photodegradation

Y Yao, Y Wang, T Lu, J Zhang, K Hu, H Zhang… - Applied Catalysis B …, 2024 - Elsevier
Photocatalysis has emerged as a prevailing and clean technology for water purification. In
this work, we developed a facile approach for fabricating in-plane carbon/carbon nitride …

Biomimetic nanofibrillar hydrogel with cell-adaptable network for enhancing cellular mechanotransduction, metabolic energetics, and bone regeneration

X **e, Z Li, X Yang, B Yang, Z Zong… - Journal of the …, 2023 - ACS Publications
The natural extracellular matrix, with its heterogeneous structure, provides a stable and
dynamic biophysical framework and biochemical signals to guide cellular behaviors. It is …

In situ modulation of intestinal organoid epithelial curvature through photoinduced viscoelasticity directs crypt morphogenesis

FM Yavitt, BE Kirkpatrick, MR Blatchley, KF Speckl… - Science …, 2023 - science.org
Spatiotemporally coordinated transformations in epithelial curvature are necessary to
generate crypt-villus structures during intestinal development. However, the temporal …

Responsive hydrogels based on triggered click reactions for liver cancer

JQ Zhu, H Wu, ZL Li, XF Xu, H **ng… - Advanced …, 2022 - Wiley Online Library
Globally, liver cancer, which is one of the major cancers worldwide, has attracted the
growing attention of technological researchers for its high mortality and limited treatment …