Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of
nanotechnology applied in the biomedical field, due to their easily tunable structure and …

Fluorescence imaging in the second near‐infrared window (NIR‐II, 1000–1700 nm) has
aroused immense attention for biomedical applications, offering exceptional advantages …

Mass transfer of bulky molecules, eg., bioenzymes, particularly for cross-scale
multibiomolecules, imposes serious challenges for microporous metal–organic frameworks …

Pharmacological activation of the stimulator of interferon genes (STING) pathway has
become a promising strategy for cancer immunotherapy. However, the insufficient tumorous …

The metabolic reprogramming of tumors requires high levels of adenosine triphosphate
(ATP) to maintain therapeutic resistance, posing a major challenge for photothermal therapy …

Nanomaterials that mimic the catalytic activity of natural enzymes in the complex biological
environment of the human body are called nanozymes. Recently, nanozyme systems have …

The complexity, diversity, and heterogeneity of malignant tumors pose a formidable
challenge for antitumor therapy. To achieve the goal of significantly enhancing the antitumor …

Metal–organic frameworks are smart carriers for controlled drug delivery due to large
surface area and adjustable pore size. Current approaches can hardly utilize the pore space …

Breaking immunosuppressive tumor microenvironment (TME) has unique effects on
inhibiting tumor growth and recurrence. Here, an endoplasmic reticulum (ER) targeted …

Photothermal therapy (PTT), which employs nanoscale transducers delivered into a tumor to
locally generate heat upon irradiation with near‐infrared light, shows great potential in killing …