Inflammation and biomaterials: role of the immune response in bone regeneration by inorganic scaffolds

JM Sadowska, MP Ginebra - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
The regulatory role of the immune system in maintaining bone homeostasis and restoring its
functionality, when disturbed due to trauma or injury, has become evident in recent years …

[HTML][HTML] A practical guide for evaluating the osteoimmunomodulatory properties of biomaterials

G Mestres, SSD Carter, NP Hailer, A Diez-Escudero - Acta biomaterialia, 2021 - Elsevier
Biomaterials offer a promising approach to repair bone defects. Whereas traditional studies
predominantly focused on optimizing the osteogenic capacity of biomaterials, less focus has …

[HTML][HTML] Calcium phosphate-based materials regulate osteoclast-mediated osseointegration

X Wang, Y Yu, L Ji, Z Geng, J Wang, C Liu - Bioactive Materials, 2021 - Elsevier
Calcium phosphate-based materials (CaP) have been widely used as bone graft substitutes
with a decent osseointegration. However, the mechanism whereby cells function and repair …

Biomimetic versus sintered macroporous calcium phosphate scaffolds enhanced bone regeneration and human mesenchymal stromal cell engraftment in calvarial …

MÁ Brennan, DS Monahan, B Brulin, S Gallinetti… - Acta biomaterialia, 2021 - Elsevier
In contrast to sintered calcium phosphates (CaPs) commonly employed as scaffolds to
deliver mesenchymal stromal cells (MSCs) targeting bone repair, low temperature setting …

[HTML][HTML] The state of the art and prospects for osteoimmunomodulatory biomaterials

AM Negrescu, A Cimpean - Materials, 2021 - mdpi.com
The critical role of the immune system in host defense against foreign bodies and pathogens
has been long recognized. With the introduction of a new field of research called …

A Biphasic Calcium Phosphate Cement Enhances Dentin Regeneration by Dental Pulp Stem Cells and Promotes Macrophages M2 Phenotype In Vitro

Y Gu, X **e, R Zhuang, MD Weir, TW Oates… - … engineering Part A, 2021 - liebertpub.com
Calcium phosphate cement (CPC) is promising for bone and dentin repair and regeneration.
However, there has been no report of biphasic CPC for inducing dentin regeneration. The …

[HTML][HTML] Osteoclast-mediated acidic hydrolysis of thermally gelled curdlan component of the bone scaffolds: Is it possible?

A Przekora, L Penolazzi, G Kalisz, P Kazimierczak… - Carbohydrate …, 2022 - Elsevier
Many biomaterials for bone regeneration have recently been produced using thermally
gelled curdlan (1, 3-β-D-glucan) as a binder for bioceramics. As the human organism does …

[HTML][HTML] Analysis of In Vitro Leukocyte Responses to Biomaterials in the Presence of Antimicrobial Porcine Neutrophil Extract (AMPNE)

B Drzewiecka, A Przekora, D Dobko, A Kozera, K Krać… - Materials, 2023 - mdpi.com
Implant insertion can evoke excessive inflammation which disrupts the healing process and
potentially leads to complications such as implant rejection. Neutrophils and macrophages …

Tissue response to biphasic calcium phosphate covalently modified with either heparin or hyaluronic acid in a mouse subcutaneous implantation model

S Stojanović, H AlKhoury, M Radenković… - … Research Part A, 2021 - Wiley Online Library
Biphasic calcium phosphate (BCP) materials are widely employed as bone substitute
materials due to their resorption/degradation properties. Inflammation after implantation of …

[PDF][PDF] The State of the Art and Prospects for Osteoimmunomodulatory Biomaterials. Materials 2021, 14, 1357

AM Negrescu, A Cimpean - 2021 - academia.edu
The critical role of the immune system in host defense against foreign bodies and pathogens
has been long recognized. With the introduction of a new field of research called …