Motile ciliopathies
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …
Kinesin superfamily motor proteins and intracellular transport
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
[HTML][HTML] Forces in tissue morphogenesis and patterning
During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …
and gene expression of cells. They are therefore integral to any morphogenetic processes …
[HTML][HTML] Brain lateralization: a comparative perspective
O Güntürkün, F Ströckens… - Physiological …, 2020 - journals.physiology.org
Comparative studies on brain asymmetry date back to the 19th century but then largely
disappeared due to the assumption that lateralization is uniquely human. Since the …
disappeared due to the assumption that lateralization is uniquely human. Since the …
[HTML][HTML] Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease
The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
Structural biology of cilia and intraflagellar transport
Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …
Overview of structure and function of mammalian cilia
P Satir, ST Christensen - Annu. Rev. Physiol., 2007 - annualreviews.org
Cilia are membrane-bounded, centriole-derived projections from the cell surface that contain
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …
Motile cilia of human airway epithelia are chemosensory
Cilia are microscopic projections that extend from eukaryotic cells. There are two general
types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert …
types of cilia; primary cilia serve as sensory organelles, whereas motile cilia exert …
[HTML][HTML] The vertebrate primary cilium in development, homeostasis, and disease
Cilia are complex structures that have garnered interest because of their roles in vertebrate
development and their involvement in human genetic disorders. In contrast to multicellular …
development and their involvement in human genetic disorders. In contrast to multicellular …
[HTML][HTML] A single-cell time-lapse of mouse prenatal development from gastrula to birth
The house mouse (Mus musculus) is an exceptional model system, combining genetic
tractability with close evolutionary affinity to humans,. Mouse gestation lasts only 3 weeks …
tractability with close evolutionary affinity to humans,. Mouse gestation lasts only 3 weeks …