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Structural biology of cilia and intraflagellar transport
Cilia are ubiquitous microtubule-based eukaryotic organelles that project from the cell to
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …
generate motility or function in cellular signaling. Motile cilia or flagella contain axonemal …
Motile ciliopathies
Motile cilia are highly complex hair-like organelles of epithelial cells lining the surface of
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …
various organ systems. Genetic mutations (usually with autosomal recessive inheritance) …
[HTML][HTML] A single-cell time-lapse of mouse prenatal development from gastrula to birth
The house mouse (Mus musculus) is an exceptional model system, combining genetic
tractability with close evolutionary affinity to humans,. Mouse gestation lasts only 3 weeks …
tractability with close evolutionary affinity to humans,. Mouse gestation lasts only 3 weeks …
[HTML][HTML] Brain lateralization: a comparative perspective
O Güntürkün, F Ströckens… - Physiological …, 2020 - journals.physiology.org
Comparative studies on brain asymmetry date back to the 19th century but then largely
disappeared due to the assumption that lateralization is uniquely human. Since the …
disappeared due to the assumption that lateralization is uniquely human. Since the …
[HTML][HTML] Forces in tissue morphogenesis and patterning
During development, mechanical forces cause changes in size, shape, number, position,
and gene expression of cells. They are therefore integral to any morphogenetic processes …
and gene expression of cells. They are therefore integral to any morphogenetic processes …
[HTML][HTML] Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease
The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …
Kinesin superfamily motor proteins and intracellular transport
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …
[HTML][HTML] A single-embryo, single-cell time-resolved model for mouse gastrulation
Mouse embryonic development is a canonical model system for studying mammalian cell
fate acquisition. Recently, single-cell atlases comprehensively charted embryonic …
fate acquisition. Recently, single-cell atlases comprehensively charted embryonic …
Microscopic artificial cilia–a review
Cilia are microscopic hair-like external cell organelles that are ubiquitously present in
nature, also within the human body. They fulfill crucial biological functions: motile cilia …
nature, also within the human body. They fulfill crucial biological functions: motile cilia …
Overview of structure and function of mammalian cilia
P Satir, ST Christensen - Annu. Rev. Physiol., 2007 - annualreviews.org
Cilia are membrane-bounded, centriole-derived projections from the cell surface that contain
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …
a microtubule cytoskeleton, the ciliary axoneme, surrounded by a ciliary membrane …