The central role of eukaryotic translation initiation factor 4E (eIF4E) in controlling mRNA
translation has been clearly assessed in the last decades. eIF4E function is essential for …

The cap‐binding protein 4EHP/eIF4E2 has been a recent object of interest in the field of post‐
transcriptional gene regulation and translational control. From ribosome‐associated quality …

Eukaryotic initiation factor 4G (eIF4G) plays a central role in translation initiation through its
interactions with the cap-binding protein eIF4E. This interaction is a major drug target for …

The eukaryotic mRNA 5′ cap structure is indispensible for pre-mRNA processing, mRNA
export, translation initiation, and mRNA stability. Despite this importance, structural and …

The eIF4E homologous protein (4EHP) is thought to repress translation by competing with
eIF4E for binding to the 5′ cap structure of specific mRNAs to which it is recruited through …

The interaction of the eukaryotic initiation factor 4G (eIF4G) with the cap-binding protein
eIF4E initiates cap-dependent translation and is regulated by the 4E-binding proteins (4E …

Piwi-interacting RNAs (piRNAs) constitute a class of small RNAs that bind PIWI proteins and
are essential to repress transposable elements in the animal germline, thereby promoting …

Abstract GIGYF (Grb10-interacting GYF [glycine–tyrosine–phenylalanine domain]) proteins
coordinate with 4EHP (eIF4E [eukaryotic initiation factor 4E] homologous protein), the DEAD …

The association-dissociation of the cap-binding protein eukaryotic translation initiation factor
4E (eIF4E) with eIF4G is a key control step in eukaryotic translation. The paradigm on the …

Abstract PixelDB, the Peptide Exosite Location Database, compiles 1966 non‐redundant,
high‐resolution structures of protein–peptide complexes filtered to minimize the impact of …